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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-05-2017 | Retinal Disorders

OCT angiography quantifying choriocapillary circulation in idiopathic macular hole before and after surgery

Authors: Yufei Teng, Marco Yu, Yi Wang, Xinxin Liu, Qisheng You, Wu Liu

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 5/2017

Abstract

Purpose

To investigate the choriocapillary circulation in the macular area for eyes with unilateral idiopathic macular hole (IMH) before and after vitrectomy using optical coherence tomography angiography (OCTA).

Methods

A prospective study of 25 patients with unilateral IMH who underwent vitrectomy and 30 age- and sex-matched healthy controls were recruited. Choriocapillary circulation was measured by OCTA to obtain two measurements: flow area and parafovea vessel density.

Results

Flow area and parafovea vessel density of choriocapillaris in the macular area were significantly smaller and lower in IMH eyes than unaffected fellow eyes and healthy control eyes (p < 0.001), while no difference was found between unaffected fellow eyes and the healthy control eyes. One month after vitrectomy, the choriocapillary flow area and parafovea vessel density of IMH eyes significantly increased compared to the peroperative measurements (p < 0.001). Association analysis found that choriocapillary circulation measurements were negatively correlated with macular hole diameters in IMH eyes (p < 0.001), but was independent with best-corrected visual acuity (BCVA).

Conclusions

The macular choriocapillary flow area and parafovea vessel density in IMH eyes were lower than those of normal controls. In addition, the choriocapillary circulation was negatively correlated with macular hole diameter. Our findings suggested that choroidal circulation in the macular area might be affected by the intact structure of the fovea.

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Title: OCT angiography quantifying choriocapillary circulation in idiopathic macular hole before and after surgery
Authors: Yufei Teng
Marco Yu
Yi Wang
Xinxin Liu
Qisheng You
Wu Liu
Publication date: 01-05-2017
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 5/2017
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-017-3586-0

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

OCT angiography quantifying choriocapillary circulation in idiopathic macular hole before and after surgery

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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