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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-07-2016 | Retinal Disorders

Recurrence of macular edema in eyes with branch retinal vein occlusion changes the diameter of unaffected retinal vessels

Authors: Jong Chan Im, Jae Pil Shin, In Taek Kim, Dong Ho Park

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 7/2016

Abstract

Purpose

To measure unaffected retinal vessel diameter in eyes with macular edema (ME) secondary to branch retinal vein occlusion (BRVO) after intravitreal injection with bevacizumab (IVB).

Methods

Patients with BRVO-induced ME who responded to IVB were assessed at baseline and 1, 3, and 6 months. In both eyes, the diameters of the largest arteriole and venule in all quadrants (except occlusion quadrant) were measured by using a computer-assisted method. The same vessels chosen at baseline were measured at each follow-up examination.

Results

Forty-two eyes were participated. At baseline, venular diameters of unaffected quadrants in eyes with BRVO were larger than the venules in the corresponding quadrant of the fellow eyes (p < 0.05, respectively). The venular diameters in all quadrants of the affected eyes decreased significantly relative to baseline after IVB (p < 0.05 respectively). Twenty-two eyes (52.4 %) developed recurrent ME. On recurrence at 3 (n = 15, 35.7 %) or 6 months (n = 7, 16.7 %), the unaffected venular diameters increased significantly (p < 0.05 respectively). These diameters again decreased significantly after a second IVB (p < 0.05 respectively).

Conclusion

Unaffected retinal venular diameters associate with the course of BRVO with ME. This may help elucidate the pathological mechanism underlying BRVO.

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Title: Recurrence of macular edema in eyes with branch retinal vein occlusion changes the diameter of unaffected retinal vessels
Authors: Jong Chan Im
Jae Pil Shin
In Taek Kim
Dong Ho Park
Publication date: 01-07-2016
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 7/2016
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-015-3175-z

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Recurrence of macular edema in eyes with branch retinal vein occlusion changes the diameter of unaffected retinal vessels

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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