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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 12/2014

01-12-2014 | Glaucoma

A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration

Authors: Randolf A. Widder, Sven Dinslage, André Rosentreter, Jens F Jordan, Pia Kühnrich, Claus Cursiefen, Klaus-Dieter Lemmen, Thomas S. Dietlein

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 12/2014

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Abstract

Background

To evaluate the potential of lowering intraocular pressure in pseudoexfoliation glaucoma with combined phacoemulsification, Trabectome, and trabecular aspiration (triple procedure) compared to phacoemulsification and trabecular aspiration alone.

Methods

Using a case-matched retrospective study design, 30 patients were included into each group. The main outcome measures were the reduction of intraocular pressure and medication score at the end of follow-up. Clinical data were collected from the patients’ medical records.

Results

Mean follow-up was 15 months in both groups. Intraocular pressure decreased from 25.3 ± 6.3 mmHg to 14.4 ± 3.7 mmHg (p < 0.0001) in the triple procedure group and from 25.3 ± 4.2 mmHg to 18.1 ± 4.2 mmHg (p < 0.0001) in the control group. The medication score was lowered from 3.4 ± 1.7 to 2.1 ± 1.2 (p = 0.0017) in the triple procedure group and from 3.8 ± 1.8 to 2.3 ± 1.5 (p < 0.008) in the control group. The reduction of intraocular pressure was higher (p < 0.004) in the triple procedure group (38.4 ± 17.3 %) compared to the control group (26.8 ± 19.6 %) The reduction of the medication score did not differ significantly.

Conclusions

The triple procedure is more effective in lowering intraocular pressure compared to phacoemulsification and trabecular aspiration alone in pseudoexfoliation glaucoma.
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Metadata
Title
A new surgical triple procedure in pseudoexfoliation glaucoma using cataract surgery, Trabectome, and trabecular aspiration
Authors
Randolf A. Widder
Sven Dinslage
André Rosentreter
Jens F Jordan
Pia Kühnrich
Claus Cursiefen
Klaus-Dieter Lemmen
Thomas S. Dietlein
Publication date
01-12-2014
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 12/2014
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-014-2795-z

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