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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-11-2014 | Retinal Disorders

A novel spectral-domain optical coherence tomography model to estimate changes in vitreomacular traction syndrome

Authors: Marco Codenotti, Lorenzo Iuliano, Giovanni Fogliato, Giuseppe Querques, Francesco Bandello

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 11/2014

Abstract

Purpose

To analyze the course of eyes with vitreomacular traction (VMT), and to find by optical coherence tomography (OCT) possible correlations between vitreomacular interface area changes and the chance of spontaneous VMT resolution.

Methods

Retrospective analysis of all consecutive patients presenting with VMT over a 24-month period. We introduced a novel OCT evaluation model to assess the vitreomacular interface area. Central foveal thickness (CFT) and best-corrected visual acuity (BCVA) were also analyzed throughout follow-up.

Results

Twenty-six eyes of 18 symptomatic patients were followed for 12.9 ± 4.8 months. Eyes were subdivided into groups according to their clinical course. Six eyes (23%) had a spontaneous resolution of the VMT (group A), and the interface area before its occurrence (39565 ± 26409 μm²) was smaller than at study entry (99434 ± 38819 μm²; p = 0.03). The interface area did not significantly change throughout follow-up in the group that underwent surgery (group B, 11 eyes) and in the group that remained overall stable (group C, 9 eyes). At baseline, the interface area was smaller in group A compared to groups with non-resolved VMT (mean values of group B and C together) (785095 ± 920721 μm²; p = 0.002). CFT and BCVA did not significantly change in any of the studied groups. Vitreomacular interface area of 101002 μm² was identified as the threshold value separating the spontaneous VMT resolution group from the group with non-resolved VMT (p < 0.001).

Conclusions

The more the vitreomacular interface area reduced over time, the higher was the chance of spontaneous VMT resolution. An area below 101002 μm² was the threshold value indicating a higher chance of spontaneous release of VMT.

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Title: A novel spectral-domain optical coherence tomography model to estimate changes in vitreomacular traction syndrome
Authors: Marco Codenotti
Lorenzo Iuliano
Giovanni Fogliato
Giuseppe Querques
Francesco Bandello
Publication date: 01-11-2014
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 11/2014
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-014-2645-z

At a glance: The STEP trials

Springer Medicine

A novel spectral-domain optical coherence tomography model to estimate changes in vitreomacular traction syndrome

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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