Unilateral intravitreal dexamethazone implant for bilateral retinitis pigmentosa-related macular edema

Excerpt

Dear Editor, I would like to congratulate Srour et al. for their case series about the treatment of macular edema (ME) secondary to retinitis pigmentosa by intravitreal dexamethasone implant (Ozurdex) (DEX implant) [1]. Retinal pigmentosa (RP) is a group of inherited retinal degenerative diseases caused by several gene abnormalities. The first lesion is peripheral, and the central vision of RP patients is relatively preserved. However, when ME occurs in these patients, central vision is often impaired. The ME could be caused by circulating anti-retinal antibodies; this suggests that an autoimmune process may be implicated in the formation of ME in RP [2]. Sustained chronic inflammatory reaction may contribute to the pathogenesis of retinal degeneration in rd10 mice, suggesting there is ocular inflammatory reaction in patients with RP [3]. In this case, a treatment by corticosteroids could be efficient. …