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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-02-2011 | Retinal Disorders

Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study

Authors: Janusz Michalewski, Zofia Michalewska, Krzysztof Dzięgielewski, Jerzy Nawrocki

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 2/2011

Abstract

Background

The pathogenesis of macular pseudohole (MPH) is supposed to be different from that of macular lamellar hole (LMH). MPH is thought to be caused by centripetal contraction of previously present epiretinal membrane. LMH is considered to be an effect of abortive process of full-thickness macular hole formation, or a result of de-roofing of a foveal cyst in persistent cystoid macular oedema. In most cases of LMH, epiretinal membranes are present. The aim of this paper is to show that LMH and MPH may have a common origin and that LMH may evolve from MPH as an epiretinal membrane contracts.

Methods

Observational two-case series of patients with MPH and epiretinal membrane. Spectral domain optical coherence tomography (SD-OCT) was performed during follow-up.

Results

In 6 months of follow-up in case 1 and 2 months in case 2, MPH progressed to non-full-thickness macular defect, fulfilling the criterion of LMH in SD-OCT. Non-vitreous interface traction was detected.

Conclusion

SD-OCT proves that MPH may progress to LMH without any vitreous traction. Progressive contraction of epiretinal membranes may be a cause of both MPH and LMH, being an advanced stage of the same non-full-thickness macular disorder.

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Title: Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study
Authors: Janusz Michalewski
Zofia Michalewska
Krzysztof Dzięgielewski
Jerzy Nawrocki
Publication date: 01-02-2011
Publisher: Springer-Verlag
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 2/2011
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-010-1463-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evolution from macular pseudohole to lamellar macular hole — spectral domain OCT study

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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