Published in:
Open Access
01-06-2016 | Journal club
Zika virus and neurology: proving cause and effect
Authors:
T. H. Massey, N. P. Robertson
Published in:
Journal of Neurology
|
Issue 6/2016
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Excerpt
‘Zika fever’ was first reported in Uganda and Tanzania in 1952. Caused by the Zika flavivirus it consisted of a mild and self-limiting illness of rash, low-grade fever, conjunctivitis, headache and myalgia. Two strains of Zika virus were subsequently identified (African and Asian) with transmission via mosquito or sexual contact. Since 2007 there have been several epidemics of the Asian strain including in French Polynesia (2013–2014; 20,000 cases) and Brazil (2015–2016; 30,000 cases), and these outbreaks have been associated with increased incidence of Guillain–Barré syndrome (GBS) in adults and microcephaly in infants. …