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01-04-2016 | Original Communication

Endovascular mechanical thrombectomy in basilar artery occlusion: variables affecting recanalization and outcome

Authors: Nicola Gilberti, Massimo Gamba, Enrico Premi, Angelo Costa, Veronica Vergani, Ilenia Delrio, Raffaella Spezi, Dikran Mardighian, Michele Frigerio, Roberto Gasparotti, Alessandro Padovani, Mauro Magoni

Published in: Journal of Neurology | Issue 4/2016

Abstract

Ischemic stroke due to basilar artery occlusion (BAO) is frequently associated with a poor prognosis. To date the most effective therapeutic approach has not been established and little is known about the predictors of clinical outcome. The aim of this study was to describe safety and efficacy of intra-arterial mechanical thrombectomy (IAMT) through latest generation devices in patients with BAO, focusing on those variables that may affect recanalization and clinical outcome. We analyzed retrospectively a series of 32 patients with BAO who underwent IAMT. We assessed the association of some clinical and neuroradiological features with recanalization rate and clinical outcome. Successful recanalization was achieved in 28 out of 32 patients (87.5 %). Symptomatic intracerebral hemorrhage (SICH) was observed in 2/32 patients (6.3 %) and mortality in the first 3 months was 25.0 %. At 3-month follow up evaluation, 13/32 patients (40.6 %) showed a good functional outcome (mRS score ≤2). There were no statistical differences in term of age, gender, risk factors, cause of stroke, recanalization rate, pre-treatment pc-ASPECTS score and SICH frequencies between patients with favorable and unfavorable outcome. Increased length of thrombi was associated with unfavorable clinical outcome at 3 months. Recanalization rate was not affected by any of the variables considered. In BAO, IAMT through newest generation devices has high recanalization rates and low complication frequencies. Length of BAO is an important predictor of clinical outcome.

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Title: Endovascular mechanical thrombectomy in basilar artery occlusion: variables affecting recanalization and outcome
Authors: Nicola Gilberti
Massimo Gamba
Enrico Premi
Angelo Costa
Veronica Vergani
Ilenia Delrio
Raffaella Spezi
Dikran Mardighian
Michele Frigerio
Roberto Gasparotti
Alessandro Padovani
Mauro Magoni
Publication date: 01-04-2016
Publisher: Springer Berlin Heidelberg
Published in: Journal of Neurology / Issue 4/2016
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-016-8047-x

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Endovascular mechanical thrombectomy in basilar artery occlusion: variables affecting recanalization and outcome

Abstract

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