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Published in: Journal of Neurology 12/2012

01-12-2012 | Short Commentary

Psoriasis during natalizumab treatment for multiple sclerosis

Authors: Jorge Millán-Pascual, Laura Turpín-Fenoll, Pablo Del Saz-Saucedo, Ignacio Rueda-Medina, Santiago Navarro-Muñoz

Published in: Journal of Neurology | Issue 12/2012

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Abstract

Beta-interferon therapy is known to trigger psoriasis, but this effect has not been previously reported for other multiple sclerosis treatments, such as natalizumab. The following is a case report. A 31-year-old woman affected by psoriasis and relapsing–remitting multiple sclerosis suffered a severe worsening of psoriasis symptoms during natalizumab treatment and acquired a drug-resistant course. This case suggests that aggravation of psoriasis might be a rare side effect of natalizumab, and that clinicians should be aware of the possibility of paradoxical activation of autoimmune diseases during its treatment.
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Metadata
Title
Psoriasis during natalizumab treatment for multiple sclerosis
Authors
Jorge Millán-Pascual
Laura Turpín-Fenoll
Pablo Del Saz-Saucedo
Ignacio Rueda-Medina
Santiago Navarro-Muñoz
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
Journal of Neurology / Issue 12/2012
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-012-6713-1

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