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Journal of Neurology
Published in: Journal of Neurology 11/2010

01-11-2010 | Letter to the Editors

Toxic leukoencephalopathy after intravenous heroin injection: a case with clinical and radiological reversibility

Authors: Corrado Villella, Raffaele Iorio, Gianluigi Conte, Anna Paola Batocchi, Pietro Bria

Published in: Journal of Neurology | Issue 11/2010

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Excerpt

Dear Sirs, …
Literature
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Wolters EC, van Wijngaarden GK, Stam FC, Rengelink H, Lousberg RJ, Schipper ME, Verbeeten B (1982) Leucoencephalopathy after inhaling “heroin” pyrolisate. Lancet 2(8310):1233–1237CrossRefPubMed
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Huang BY, Castillo M (2008) Hypoxic-ischemic brain injury: imaging findings from birth to adulthood. Radiographics 28:417–439CrossRefPubMed
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Chen CY, Lee KW, Chin SC, Chung HW, Zimmermann RA (2000) Heroin-induced spongiform leukoencephalopathy: value of diffusion MR imaging. J Comput Assist Tomogr 24:735–737CrossRefPubMed
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Blasel S, Hattingen E, Adelmann M, Nichtweiss M, Zanella F, Weidauer S (2010) Toxic leukoencephalopathy after heroin abuse without heroin vapour inhalation. Clin Neuroradiol 20:48–53CrossRef
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Rook EJ, van Ree JM, van den Brink W, Hillebrand MJX, Huiteman ADR, Hendriks VM, Beijnen JH (2006) Pharmacokinetics and pharmacodynamics of high doses of pharmaceutically prepared heroin, by intravenous or by inhalation route in opioid-dependent patients. Basic Clin Pharmacol Toxicol 98:86–96CrossRefPubMed
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Klous MG, Lee W, Hillebrand MJ, van den Brink W, van Ree JM, Beijnen JH (2006) Analysis of diacetylmorphine, caffeine, and degradation products after volatilization of pharmaceutical heroin for inhalation. J Anal Toxicol 30:6–13PubMed
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Gulowsen Celius E, Andersson S (1996) Leucoencephalopathy after inhalation of heroin: a case report. J Neurol Neurosurg Psychiatry 60:694–695CrossRef
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Mildh LH, Tuomisto LM, Scheinin M, Kirvela OA (2000) Morphine-induced cardiovascular stimulation: the effects of two doses on healthy subjects. Anesth Analg 91:51–57CrossRefPubMed
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McKinney AM, Kieffer SA, Paylor RT, SantaCruz KS, Kendi A, Lucato L (2009) Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR Imaging. AJR Am J Roentgenol 193:192–206CrossRefPubMed
Metadata
Title
Toxic leukoencephalopathy after intravenous heroin injection: a case with clinical and radiological reversibility
Authors
Corrado Villella
Raffaele Iorio
Gianluigi Conte
Anna Paola Batocchi
Pietro Bria
Publication date
01-11-2010
Publisher
Springer-Verlag
Published in
Journal of Neurology / Issue 11/2010
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-010-5620-6

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