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Open Access 01-09-2007 | ORIGINAL COMMUNICATION

Functioning of patients with chronic idiopathic axonal polyneuropathy (CIAP)

Authors: Peter G. Erdmann, PT, MSc, Laurien L. Teunissen, MD, PhD, Frank R. van Genderen, MSc, PhD, Nicolette C. Notermans, MD, PhD, Eline Lindeman, MD, PhD, Paul J. M. Helders, PT, MSc, PhD, Nico L. U. van Meeteren, PT, PhD

Published in: Journal of Neurology | Issue 9/2007

Abstract

Although patients with Chronic Idiopathic Axonal Polyneuropathy (CIAP) report a slow deterioration of sensory and motor functions, the impact of this deterioration on daily functioning has not yet been investigated in detail. The first aim of this crosssectional study involving 56 patients with CIAP was, therefore, to assess patients’ functioning with use of the International Classification of Functioning, Disability and Health (ICF). The second aim was to find determinants of walking ability, dexterity, and autonomy. Fatigue and limited walking ability were present in most patients and differed considerably. In regression models, age, muscle strength, and fatigue together explained 63% of the variance in walking ability, which by itself explained almost 50% of the variance in patients’ autonomy indoors and outdoors (42% and 49%, respectively). Muscle strength and sensory function scores together explained 30% of the variance in dexterity scores, which in turn explained only 13% of the variance in autonomy indoors. The diminished autonomy of patients with CIAP might be improved by reducing fatigue, by means of training, and by improving walking ability.

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Title: Functioning of patients with chronic idiopathic axonal polyneuropathy (CIAP)
Authors: Peter G. Erdmann, PT, MSc
Laurien L. Teunissen, MD, PhD
Frank R. van Genderen, MSc, PhD
Nicolette C. Notermans, MD, PhD
Eline Lindeman, MD, PhD
Paul J. M. Helders, PT, MSc, PhD
Nico L. U. van Meeteren, PT, PhD
Publication date: 01-09-2007
Publisher: Steinkopff-Verlag
Published in: Journal of Neurology / Issue 9/2007
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-006-0501-8

At a glance: The STEP trials

Springer Medicine

Functioning of patients with chronic idiopathic axonal polyneuropathy (CIAP)

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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