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Published in: Journal of Neurology 3/2007

01-03-2007 | LETTER TO THE EDITORS

Posterior horn varicella-zoster virus myelitis

Authors: R. Toledano, J. López-Sendón, F. Gilo, E. Riva, J. Martínez-San Millán, J. Masjuán

Published in: Journal of Neurology | Issue 3/2007

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Excerpt

Sirs: The Varicella–Zoster virus (VZV) is an exclusively human herpes virus that causes varicella, becomes latent in the cranial-nerve and the dorsal-root ganglia, and frequently reactivates decades later to produce shingles (zoster) and postherpetic neuralgia. In immunocompetent elderly persons or immunocompromised patients, VZV may produce central nervous system diseases [1]. Myelitis is a relatively rare neurological complication of VZV that usually develops in immunocompromised patients, particularly those with cancer or acquired immunodeficiency syndrome [13]. We report a case in which radiological findings are consistent with the spread of the virus from the dorsal root ganglia to the spinal cord through the posterior horn. To the best of our knowledge, no image showing this pattern has previously been published. …
Literature
1.
go back to reference Gilden DH, Kleinschmidt-Demasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ (2000) Neurological complications of the reactivation of varicella-zoster virus. N Engl J Med 342:635–645PubMedCrossRef Gilden DH, Kleinschmidt-Demasters BK, LaGuardia JJ, Mahalingam R, Cohrs RJ (2000) Neurological complications of the reactivation of varicella-zoster virus. N Engl J Med 342:635–645PubMedCrossRef
2.
3.
go back to reference Gray F, Bélec L, Lescs MC, Chrétien F, Ciardi A, Hassine D, et al. (1994) Varicella-zoster virus infection of the central nervous system in the acquired immune deficiency syndrome. Brain 117:987–999PubMedCrossRef Gray F, Bélec L, Lescs MC, Chrétien F, Ciardi A, Hassine D, et al. (1994) Varicella-zoster virus infection of the central nervous system in the acquired immune deficiency syndrome. Brain 117:987–999PubMedCrossRef
4.
go back to reference Sauerbrei A, Wutzler P (2002) Laboratory diagnosis of central nervous system infections caused by herpesviruses. J Clin Virol 25 Suppl 1:S45–51PubMedCrossRef Sauerbrei A, Wutzler P (2002) Laboratory diagnosis of central nervous system infections caused by herpesviruses. J Clin Virol 25 Suppl 1:S45–51PubMedCrossRef
5.
go back to reference Gilden DH, Bennett JL, Kleinschmidt-Demasters BK, Song DD, Yee AS, Steiner I (1998) The value of cerebrospinal fluid antiviral antibody in the diagnosis of neurologic disease produced by varicella zoster virus. J Neurol Sci 159:140–144PubMedCrossRef Gilden DH, Bennett JL, Kleinschmidt-Demasters BK, Song DD, Yee AS, Steiner I (1998) The value of cerebrospinal fluid antiviral antibody in the diagnosis of neurologic disease produced by varicella zoster virus. J Neurol Sci 159:140–144PubMedCrossRef
6.
go back to reference Gilden DH, Beinlich BR, Rubinstien EM, Stommel E, Swenson R, Rubinstein D, et al. (1994) Varicella-zoster virus myelitis: An expanding spectrum. Neurology 44:1818–1823PubMed Gilden DH, Beinlich BR, Rubinstien EM, Stommel E, Swenson R, Rubinstein D, et al. (1994) Varicella-zoster virus myelitis: An expanding spectrum. Neurology 44:1818–1823PubMed
7.
go back to reference Weber T, Frye S, Bodemer M, Otto M, Luke W (1996) Clinical implications of nucleic acid amplification methods for the diagnosis of viral infections of the nervous system. J Neurovirol 2:175–90PubMed Weber T, Frye S, Bodemer M, Otto M, Luke W (1996) Clinical implications of nucleic acid amplification methods for the diagnosis of viral infections of the nervous system. J Neurovirol 2:175–90PubMed
8.
go back to reference Kleinschmidt-DeMasters BK, Gilden DH (2001) Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates. Arch Pathol Lab Med 125:770–80PubMed Kleinschmidt-DeMasters BK, Gilden DH (2001) Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates. Arch Pathol Lab Med 125:770–80PubMed
9.
go back to reference Samuraki M, Yoshita M, Yamada M (2005) MRI of segmental zoster paresis. Nenurology 64:1138 Samuraki M, Yoshita M, Yamada M (2005) MRI of segmental zoster paresis. Nenurology 64:1138
10.
go back to reference Hirai T, Korogi Y, Hamatake S, Kushima I, Shigematsu Y, Takahashi M, et al. (1996) Case report: Varicella-zoster virus myelitis-serial MR findings. Br J Radiol 69:1187–1190PubMedCrossRef Hirai T, Korogi Y, Hamatake S, Kushima I, Shigematsu Y, Takahashi M, et al. (1996) Case report: Varicella-zoster virus myelitis-serial MR findings. Br J Radiol 69:1187–1190PubMedCrossRef
11.
go back to reference Ikeda K, Deguchi K, Touge T, Sasaki I, Tsukaguchi M, Shimamura M, et al. (2004) Painful legs and moving toes syndrome associated with herpes zoster myelitis. J Neurol Sci 219:147–150PubMedCrossRef Ikeda K, Deguchi K, Touge T, Sasaki I, Tsukaguchi M, Shimamura M, et al. (2004) Painful legs and moving toes syndrome associated with herpes zoster myelitis. J Neurol Sci 219:147–150PubMedCrossRef
Metadata
Title
Posterior horn varicella-zoster virus myelitis
Authors
R. Toledano
J. López-Sendón
F. Gilo
E. Riva
J. Martínez-San Millán
J. Masjuán
Publication date
01-03-2007
Publisher
Steinkopff-Verlag
Published in
Journal of Neurology / Issue 3/2007
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-006-0393-7

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