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01-07-2020 | Population Data

Forensic effectiveness and genetic distribution of 20 non-CODIS STRs and D3S1358 in Guangdong Han population

Authors: Hanhui Peng, Xiaopeng Li, Ting Yao, Hongyan Huang, Cheng Xiao, Weibin Wu, Ling Chen

Published in: International Journal of Legal Medicine | Issue 4/2020

Abstract

In this study, Guangdong Han population was analyzed with Goldeneye™ DNA ID 22NC Kit containing 20 non-CODIS STR loci and a CODIS STR locus. In 503 unrelated individuals, a total of 232 alleles and 813 genotypes were observed. The values of polymorphism information content (PIC), expected heterozygosity (He), and observed heterozygosity (Ho) ranged from 0.6678 to 0.8618, 0.7197 to 0.8757, and 0.6938 to 0.8767, respectively. No deviation from Hardy-Weinberg equilibrium was observed at all loci after the Bonferroni correction. The combined power of discrimination and the combined power of exclusion were 0.999999999999999999999999937051 and 0.999999998467033, respectively. Population comparison revealed that Guangdong Han population was relatively close to Huadong Han population. These results suggested that the 21 STR loci are highly polymorphic and Goldeneye™ DNA ID 22NC Kit is suitable for individual identification and paternity testing in Guangdong Han population.

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Title: Forensic effectiveness and genetic distribution of 20 non-CODIS STRs and D3S1358 in Guangdong Han population
Authors: Hanhui Peng
Xiaopeng Li
Ting Yao
Hongyan Huang
Cheng Xiao
Weibin Wu
Ling Chen
Publication date: 01-07-2020
Publisher: Springer Berlin Heidelberg
Published in: International Journal of Legal Medicine / Issue 4/2020
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-019-02094-1

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Forensic effectiveness and genetic distribution of 20 non-CODIS STRs and D3S1358 in Guangdong Han population

Abstract

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Abstract

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