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01-11-2016 | Population Data

Phylogenetic and forensic studies of the Bangladeshi population using next-generation PowerPlex® Y23 STR marker system

Authors: Md. Mahamud Hasan, Pilu Momtaz, Tania Hossain, Ashish Kumar Mazumder, Md. Jabedul Alam Khondaker, Abu Sufian, Md. Niaz Makhdum, Sharif Akhteruzzaman

Published in: International Journal of Legal Medicine | Issue 6/2016

Abstract

Haplotype diversity and allele frequencies of 23 Y chromosomal short tandem repeat (STR) loci included in the next-generation PowerPlex® Y23 System were studied in 137 Bangladeshi Bengali males. A total of 134 different haplotypes were observed with a discrimination capacity (DC) of 0.978, indicating a high potential for differentiating between male individuals in this population. The highest allele frequency (0.818) was observed in locus DYS391. Locus DYS385a/b showed the highest gene diversity (0.945) while locus DYS391 showed the lowest gene diversity (0.302). Double alleles were detected in three loci. On the other hand, four null alleles were detected in a single haplotype at DYS448, DYS549, DYS392, and DYS385a/b locus, respectively. The haplotype data is available in the Y chromosome haplotype reference database under accession number YA003445. To understand the genetic diversity of Bangladeshi Bengali population, a pairwise genetic distances (Rst) was calculated by comparing with 23 population studies consisting 4249 haplotypes. The analysis placed the Bangladeshi population along with Indian Tamil and Indo-Pakistani population in a clade separated from the rest.

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Carlson RV, Boyd KM, Webb DJ (2004) The revision of the Declaration of Helsinki: past, present and future. Br J Clin Pharmacol 57:695–713CrossRefPubMedPubMedCentral

Walsh PS, Metzger DA, Higuchi R (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 10:506–518PubMed

Gusmão L, Butler JM, Carracedo A, Gill AP, Kayser M, Mayr WR, Morling N, Prinz M, Roewer L, Tyler Smith C, Schneider PM (2006) DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendation on the use of Y-STRs in forensic analysis. Forensic Sci Int 157:187–197CrossRefPubMed

Nei M (1987) Molecular Evolutionary Genetics. Columbia University Press, New York, p 178

Butler JM, Decker AE, Kline MC, Vallone PM (2005) Chromosomal duplication along the Y-Chromosome and their potential impact on Y-STR interpretation. J Forensic Sci 50(4):853–859PubMed

Balaresque P, Bowden GR, Parkin EJ, Omran GA, Heyer E, Quintana-Murci L, Rower L, Stoneking M, Nasidze I, Carvalho-Silva DR, Tyler-Smith C, de Kniff P, Jobling MA (2008) Dynamic nature of the proximal AZFc region of the human Y chromosome: multiple independent deletion and duplication events revealed by microsatellite analysis. Hum Mutat 20(10):1171–80CrossRef

Chang YM, Perumal R, Keat PY, Kuehn DL (2007) Haplotype diversity of 16 Y-chromosomal STR in three main ethnic populations (Malays, Chinese and Indians) in Malaysia. Forensic Sci Int 167:70–76CrossRefPubMed

Park MJ, Kraayenbrink T, Opgenort JR, van Driem GL, Tuladhar NM, de Knijff P, Jobling MA (2007) Diversity of 26-locus Y-STR haplotypes in a Nepalese population sample: isolation and drift in the Himalayas. Forensic Sci Int 166:176–181CrossRef

Park MJ, Kyoung-Jin S, Kim NY, Yang YI, Cho SH, Lee HY (2008) Characterization of deletion in DYS385 flanking region and null alleles associated with AZFc microdeletions in Koreans. J Forensic Sci 53:331–334CrossRefPubMed

10.

Budowle B, Aranda XG, Lagace RE, Hennessy LK, Planz JV, Rodriguez M, Eisenberg AJ (2008) Null allele sequence structure at the DYS448 locus and implications for profile interpretation. Int J Leg Med 122:421–427CrossRef

11.

Westen AA, Kraaijenbrink T, Robles de Medina EA, Harteveld J, Willemse P, Zuniga SB, van der Gaag KJ, Weiler NE, Warnaar J, Kayser M, Sijen T, de Knijff P (2014) Comparing six commercial autosomal STR kits in a large Dutch population sample. Forensic Sci Int Genet 10:55–63CrossRefPubMed

12.

Willuweit S, Roewer L (2007) Y chromosome haplotype reference database (YHRD): update. Forensic Sci Int Genet 1(2):83–87CrossRefPubMed

Title: Phylogenetic and forensic studies of the Bangladeshi population using next-generation PowerPlex® Y23 STR marker system
Authors: Md. Mahamud Hasan
Pilu Momtaz
Tania Hossain
Ashish Kumar Mazumder
Md. Jabedul Alam Khondaker
Abu Sufian
Md. Niaz Makhdum
Sharif Akhteruzzaman
Publication date: 01-11-2016
Publisher: Springer Berlin Heidelberg
Published in: International Journal of Legal Medicine / Issue 6/2016
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-016-1367-7

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Phylogenetic and forensic studies of the Bangladeshi population using next-generation PowerPlex® Y23 STR marker system

Abstract

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Abstract

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