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01-11-2012 | Case Report

Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin

Authors: Benno Hartung, Hans F. Merk, Wolfgang Huckenbeck, Thomas Daldrup, Eva Neuen-Jacob, Stefanie Ritz-Timme

Published in: International Journal of Legal Medicine | Issue 6/2012

Abstract

Isotretinoin is considered to be a safe and effective therapy in otherwise therapy-resistant acne. Elevated serum creatine phosphokinase values with or without muscle-related symptoms in isotretinoin-treated patients have been reported and interpreted as benign phenomena, lethal cases have not been described yet. We present the case of a 20-year-old male who died from severe generalised rhabdomyolysis associated with isotretinoin treatment.

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Title: Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin
Authors: Benno Hartung
Hans F. Merk
Wolfgang Huckenbeck
Thomas Daldrup
Eva Neuen-Jacob
Stefanie Ritz-Timme
Publication date: 01-11-2012
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 6/2012
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-012-0750-2

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Severe generalised rhabdomyolysis with fatal outcome associated with isotretinoin

Abstract

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Abstract

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