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01-03-2011 | Review Article

The new influenza A (H1N1/09): symptoms, diagnostics, and autopsy results

Authors: Carolin Edler, A. Klein, A. Gehl, C. Ilchmann, S. Scherpe, M. Schrot

Published in: International Journal of Legal Medicine | Issue 2/2011

Abstract

The first infections of the new H1N1 (“swine flu”) virus were announced in April 2009. Soon after, case numbers were observed to be climbing virtually worldwide. In most cases, infections appeared rather mild with typical flu symptoms. In contrast to the seasonal flu, however, cases with vomiting and diarrhea were also reported, and the affected age group seemed to be younger. Sudden and fatal progression affected mostly those under 60 years of age. The autopsy reports of two fatalities with the new influenza are discussed. Multiple postmortem swabs from the nose and throat area determined the H1N1-RNA.

Blyth CC, Iredell JR, Dwyer DE (2009) Rapid-test sensitivity for novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 361:25CrossRef

Bundesministerium für Gesundheit (2009) Verordnung zur Änderung über die Meldepflicht bei Influenza, die durch das erstmals im April 2009 in Nordamerika aufgetretene neue Virus (“Schweine-Grippe”) hervorgerufen wird. [Internet] http://www.kvberlin.de/20praxis/70themen/pandemie/flu_verord_meldepflicht_aend.pdf [15.12.2009 12:30]

CDC (2009) Post-mortem care and safe autopsy procedures for novel H1N1 influenza. [Internet] URL: http://www.cdc.gov/h1n1flu/post_mortem.htm [11.01.2010 15:00]

Mauad et al (2010) Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med 181:72–79CrossRef

Panning M, Eickmann M, Landt O et al (2009) Detection of influenza A(H1N1)v virus by real time RT-PCR. Eur Surveill 14(18):19329

Ramsthaler F, Verhoff MA, Gehl A, Kettner M (2010) The novel H1N1/swine-origin influenza virus and its implications for autopsy practice. Int J Legal Med 124:171–173PubMedCrossRef

RKI (2009) Influenza-Wochenbericht—Kalenderwoche 48. [Internet] URL: http://influenza.rki.de/Wochenberichte/2009-48.pdf [15.12.2009 12:00]

RKI (2009) Influenza-Wochenbericht—Kalenderwoche 51. [Internet] URL: http://influenza.rki.de/Wochenberichte/2009-51.pdf [15.12.2009 12:00]

RKI (2009) Influenza (Saisonale Influenza, Neue (pandemische) Influenza A/H1N1, Aviäre Influenza). [Internet] URL: http://www.rki.de/nn_200120/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber__Mbl__Influenza.html [10.12.2009 16:00]

10.

RKI (2009) Grundsätze zur Indikation von diagnostischen Testverfahren bei Neuer Influenza A/H1N1. [Internet] URL: http://www.rki.de/nn_200120/DE/Content/InfAZ/I/Influenza/IPV/Stellungnahme__Diagnostik.html [05.01.2010 14:00]

11.

RKI (2009) Mitteilung der Ständigen Impfkommission (STIKO) am RKI. Impfung gegen die Neue Influenza A (H1N1). [Internet] URL: http://www.rki.de/cln_169/nn_200120/DE/Content/Infekt/EpidBull/Archiv/2009/50__09,templateId=raw,property=publicationFile.pdf/50_09.pdf [08.01.2010 16:00]

12.

Royal College of Pathologists (2009) Advice for pathologists and anatomical pathology technologists for autopsy of cadavers with known or suspected new/virulent strains of influenza A (3rd edition) [Internet] URL: http://www.rcpath.org/resources/pdf/g020adviceautopsyinfluenzaaoct09.pdf [11.01.2010 17:00]

13.

Schwinger RHG, Reuter H (2005) Virale Herzerkrankungen. In: Erdmann E (ed) Klinische Kardiologie, 6th edn. Springer, Heidelberg, pp 619–640

14.

Winzer et al (2009) Erste klinische Erfahrungen mit der Neuen Influenza A (H1N1/09). Dtsch Arztbl Int 106(47):770–776

Title: The new influenza A (H1N1/09): symptoms, diagnostics, and autopsy results
Authors: Carolin Edler
A. Klein
A. Gehl
C. Ilchmann
S. Scherpe
M. Schrot
Publication date: 01-03-2011
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 2/2011
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-010-0504-y

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The new influenza A (H1N1/09): symptoms, diagnostics, and autopsy results

Abstract

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