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Published in: Lung 2/2018

01-04-2018 | Lung Images

Lung Image: Doege–Potter Syndrome

Authors: Sami Karapolat, Kubra Nur Seyis, Alaaddin Buran, Atila Turkyilmaz, Safak Ersoz, Celal Tekinbas

Published in: Lung | Issue 2/2018

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Excerpt

A 37-year-old male patient presented to an external clinic reporting dyspnea, fatigue, dizziness, and intermittent episodes of syncope. Upon blood testing, he was found to have hypoglycemia. His anamnesis revealed a surgical procedure and radiotherapy was performed 6 years prior due to a solitary fibrous tumor in his right hemithorax. He had no history of diabetes or medication at all. The patient was somnolent and his blood pressure was 125/80 mmHg, pulse was 95 bpm, and breathing rate was 19 breaths/min. Upon auscultation, no respiratory sounds were heard in the right hemithorax. His blood glucose level was approximately 50 mg/dL and his serum insulin level was 3.4 μU/mL. An intravenous infusion of 50% glucose was performed in an attempt to keep the patient’s blood glucose level within normal limits. Upon chest X-ray, opacity was observed in his right hemithorax. During thoracic tomography, a giant heterogeneous mass was seen in his right hemithorax (Fig. 1). No FDG uptake was observed in PET–CT scans (Fig. 2). The patient was reported to have a solitary fibrous tumor following a transthoracic fine-needle aspiration biopsy. A total excision of the mass and pleura with right redo posterolateral thoracotomy was performed next (Fig. 3). The patient’s blood glucose level remained within normal limits in the postoperative period. He was discharged on postoperative day 8. Macroscopic examination of the specimen revealed that it had well-circumscribed, smooth-surfaced, and capsulated large lobular masses. Following a histopathological examination, the patient was diagnosed with a malignant solitary fibrous tumor of the pleura with pleomorphism and high cellularity (Fig. 4). After a year of follow-up visits, the patient was still asymptomatic. …
Literature
1.
go back to reference Jang JG, Chung JH, Hong KS, Ahn JH, Lee JY, Jo JH, Lee DW, Shin KC, Lee KH, Kim MJ, Lee JC, Lee JH, Lee JK (2015) A case of solitary fibrous pleura tumor associated with severe hypoglycemia: Doege-Potter syndrome. Tuberc Respir Dis 78(2):120–124CrossRef Jang JG, Chung JH, Hong KS, Ahn JH, Lee JY, Jo JH, Lee DW, Shin KC, Lee KH, Kim MJ, Lee JC, Lee JH, Lee JK (2015) A case of solitary fibrous pleura tumor associated with severe hypoglycemia: Doege-Potter syndrome. Tuberc Respir Dis 78(2):120–124CrossRef
2.
go back to reference Degnan AJ, Lee KK, Minervini MI, Borhani AA (2016) Metastatic extrapleural malignant solitary fibrous tumor presenting with hypoglycemia (Doege-Potter syndrome). Radiol Case Rep 12(1):113–119CrossRefPubMedPubMedCentral Degnan AJ, Lee KK, Minervini MI, Borhani AA (2016) Metastatic extrapleural malignant solitary fibrous tumor presenting with hypoglycemia (Doege-Potter syndrome). Radiol Case Rep 12(1):113–119CrossRefPubMedPubMedCentral
3.
go back to reference Villemain A, Menard O, Mandry D, Siat J, Vignaud JM, Martinet Y, Tiotiu A (2017) Paraneoplastic hypoglycemia: the hopes of pathophysiological documentation. Rev Pneumol Clin. 73(3):140–145CrossRefPubMed Villemain A, Menard O, Mandry D, Siat J, Vignaud JM, Martinet Y, Tiotiu A (2017) Paraneoplastic hypoglycemia: the hopes of pathophysiological documentation. Rev Pneumol Clin. 73(3):140–145CrossRefPubMed
Metadata
Title
Lung Image: Doege–Potter Syndrome
Authors
Sami Karapolat
Kubra Nur Seyis
Alaaddin Buran
Atila Turkyilmaz
Safak Ersoz
Celal Tekinbas
Publication date
01-04-2018
Publisher
Springer US
Published in
Lung / Issue 2/2018
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-017-0078-2

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