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Published in:

01-08-2017

Clinically Promising Biomarkers in Cystic Fibrosis Pulmonary Exacerbations

Authors: L. Keith Scott, Robert Toner

Published in: Lung | Issue 4/2017

Abstract

Cystic fibrosis is a complex genetic disease hallmarked by repetitive infectious exacerbations that leads to destruction of airway architecture, acute on chronic inflammatory changes, and deterioration in lung function. Predicting an exacerbation may help preempt some of these changes by the initiation of swift antibiotic and anti-inflammatory therapy. A search for biomarkers that could predict exacerbations or help guide duration of antibiotic therapy is being aggressively sought. In this review, we discuss the most recent and promising biomarkers that hopefully will assist in the future management of the CF patient.

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Title: Clinically Promising Biomarkers in Cystic Fibrosis Pulmonary Exacerbations
Authors: L. Keith Scott
Robert Toner
Publication date: 01-08-2017
Publisher: Springer US
Published in: Lung / Issue 4/2017
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI: https://doi.org/10.1007/s00408-017-0024-3

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