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European Archives of Oto-Rhino-Laryngology

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01-10-2020 | Coronavirus | Short Communication

Acetic acid disinfection as a potential adjunctive therapy for non-severe COVID-19

Authors: L. Pianta, A. Vinciguerra, G. Bertazzoni, R. Morello, F. Mangiatordi, V. J. Lund, M. Trimarchi

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2020

Abstract

Purpose

SARS-CoV-2 is a new pandemic influenza caused by a coronavirus which main route of transmission is through exhaled droplets that primarily infect the nose and the nasopharynx. The aim of this paper is to evaluate the effect of acetic acid, the active component of vinegar, as a potential disinfectant agent for upper airways.

Methods

Twenty-nine patients were enrolled and divided into two groups: group 1 (14 patients) was composed of patients treated with off-label hydroxychloroquine and lopinavir/ritonavir, whereas group 2 (15 patients) was composed of patients treated with hydroxychloroquine only, combined with the inhalation of acetic acid disinfectant at a 0.34% concentration. A questionnaire-based evaluation of symptoms was performed after 15 days in both groups.

Results

It appears that the number of patients treated with acetic acid (group 2) that experienced improvement in individual symptoms was double that of the other group of patients (group 1), although numbers are too small for robust statistical analysis.

Conclusions

Considering its potential benefits and high availability, acetic acid disinfection appears to be a promising adjunctive therapy in cases of non-severe COVID-19 and deserves further investigation.

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10.

Società Italiana di Malattie Infettive e Tropicali (SIMIT) (2020) Vademecum per la cure delle persone con malattia da COVID-19. Italian Guidelines, 2 ed. March 2020

Title: Acetic acid disinfection as a potential adjunctive therapy for non-severe COVID-19
Authors: L. Pianta
A. Vinciguerra
G. Bertazzoni
R. Morello
F. Mangiatordi
V. J. Lund
M. Trimarchi
Publication date: 01-10-2020
Publisher: Springer Berlin Heidelberg
Keywords: Coronavirus
Ritonavir
SARS-CoV-2
COVID-19
Hydroxychloroquine
Published in: European Archives of Oto-Rhino-Laryngology / Issue 10/2020
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-020-06067-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Acetic acid disinfection as a potential adjunctive therapy for non-severe COVID-19

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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