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Published in: European Archives of Oto-Rhino-Laryngology 10/2019

01-10-2019 | Dysphonia | Review Article

The surgical treatment of unilateral vocal cord paralysis (UVCP): qualitative review analysis and meta-analysis study

Authors: F. Granato, F. Martelli, L. V. Comini, P. Luparello, S. Coscarelli, O. Le Seac, S. Carucci, P. Graziani, R. Santoro, G. Alderotti, M. R. Barillari, Giuditta Mannelli

Published in: European Archives of Oto-Rhino-Laryngology | Issue 10/2019

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Abstract

Purpose

The objectives of this meta-analysis were to summarize the key surgical procedures for UVCP and to evaluate which of these is associated with better results in terms of vocal improvement.

Methods

A systematic review of the literature was conducted in search of articles focused on the comparison of voice outcome between different techniques for the UVCP treatment. Then, a quantitative analysis was carried out for papers published from 2013 onwards, reporting only adult patients with unilateral paralysis for each study, and each surgical technique was evaluated for its capability of achieving good functional outcomes in terms of GRBAS-I scale and maximum phonation time in seconds (MPT).

Results

The search identified 1853 publications. A total of 159 articles were stratified and included according to our selection criteria. 21 out of 159 articles were selected for quantitative synthesis. For trans-oral techniques: the mean GRBAS-I scale were 2.33 before injection and 0.41 after injection. The mean MPT before injection were 4.78 and 12.50 after injection. For open techniques the mean GRBAS-I scale were 2.43 before surgery and 0.68 after surgery. For open technique, the mean MPT were 3.50 before surgery and 12.40 after surgery.

Conclusions

The two types of techniques lead to an improvement in terms of vocal outcomes emphasizing that from the examined literature an indication emerges to perform an early injection because this could reduce the possible need for a more invasive intervention of permanent medialization in the future.
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Metadata
Title
The surgical treatment of unilateral vocal cord paralysis (UVCP): qualitative review analysis and meta-analysis study
Authors
F. Granato
F. Martelli
L. V. Comini
P. Luparello
S. Coscarelli
O. Le Seac
S. Carucci
P. Graziani
R. Santoro
G. Alderotti
M. R. Barillari
Giuditta Mannelli
Publication date
01-10-2019
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 10/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05587-2

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