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European Archives of Oto-Rhino-Laryngology
Published in: European Archives of Oto-Rhino-Laryngology 7/2019

Open Access 01-07-2019 | Care | Head & Neck

Non-curative treatment of patients with oral tongue squamous-cell carcinoma

Authors: R. Mroueh, A. Haapaniemi, T. Saarto, L. Grönholm, R. Grénman, T. Salo, A. A. Mäkitie

Published in: European Archives of Oto-Rhino-Laryngology | Issue 7/2019

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Abstract

Purpose

Late-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival.

Methods

All patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005–2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan–Meier method in this population-based study.

Results

Eighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7 months (median 2 and range 0–26).

Conclusions

Due to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.
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Metadata
Title
Non-curative treatment of patients with oral tongue squamous-cell carcinoma
Authors
R. Mroueh
A. Haapaniemi
T. Saarto
L. Grönholm
R. Grénman
T. Salo
A. A. Mäkitie
Publication date
01-07-2019
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 7/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05456-y

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