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European Archives of Oto-Rhino-Laryngology

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01-06-2019 | Otology

Effect of acoustic features on discrimination ability in individuals with auditory neuropathy spectrum disorder: an electrophysiological and behavioral study

Authors: Kumari Apeksha, U. Ajith Kumar

Published in: European Archives of Oto-Rhino-Laryngology | Issue 6/2019

Abstract

Purpose

The present study aimed to investigate the discrimination ability for acoustic cues in individuals with auditory neuropathy spectrum disorder (ANSD) using both behavioral and neural measures and to compare the result with normal hearing individuals.

Methods

Four naturally produced syllables /ba/, /da/, /ma/ and /pa/ were used to study discrimination skills. They were combined in pairs such that the two syllables differ in acoustic features, that is place (/ba/–/da/), manner (/ba/–/ma/) and voicing (/ba/–/pa/) cues. Thirty individuals with ANSD and 30 individuals with normal hearing sensitivity were the participants. Syllable discrimination skill was assessed using behavioral (reaction time, sensitivity and D-prime) and neural (P300) measures.

Results

There was prolongation in latency and reduction in amplitude of P300 in individuals with ANSD compared to individuals with normal hearing sensitivity. Individuals with ANSD showed better discrimination skill for stimulus pairs differing in the manner followed by place and the least perceived was voicing information.

Conclusion

Discrimination ability of individuals with ANSD is found to be affected as evident on behavioral and neural measures. The discrimination ability varies with acoustic features of speech.

Starr A, Picton T, Sininger Y et al (1996) Auditory neuropathy. Brain 119:741–753. https://doi.org/10.1093/brain/119.3.741 CrossRefPubMed

Berlin C, Hood L, Morlet T et al (2010) Multi-site diagnosis and management of 260 patients with auditory neuropathy/dys-synchrony (auditory neuropathy spectrum disorder). Int J Audiol 49:30–43. https://doi.org/10.3109/14992020903160892 CrossRefPubMed

Penido R, Isaac M (2013) Prevalence of auditory neuropathy spectrum disorder in an auditory health care service. Braz J Otorhinolaryngol 79:429–433. https://doi.org/10.5935/1808-8694.20130077 CrossRefPubMed

Rance G, David B, Barbara C et al (1999) Clinical findings for a group of infants and young children with auditory neuropathy. Ear Hear 20:238–252. https://doi.org/10.1097/00003446-199906000-00006 CrossRefPubMed

Narne VK, Vanaja CS (2009) Perception of speech with envelope enhancement in individuals with auditory neuropathy and simulated loss of temporal modulation processing. Int J Audiol 48:700–707. https://doi.org/10.1080/14992020902931574 CrossRefPubMed

Narne VK (2013) Temporal processing and speech perception in noise by listeners with auditory neuropathy. PLoS ONE 8:e55995. https://doi.org/10.1371/journal.pone.0055995 CrossRefPubMedPubMedCentral

Picton T (2013) Hearing in time: evoked potential studies of temporal processing. Ear Hear 34:385–401. https://doi.org/10.1097/AUD.0b013e31827ada02 CrossRefPubMed

Starr A, Picton TW, Kim R (2001) Pathophysiology of auditory neuropathy. In: Sininger Y, Starr A (eds) Auditory neuropathy: a new perspective on hearing disorders. Singular, San Diego, pp 67–82

Moser T, Starr A (2016) Auditory neuropathy—neural and synaptic mechanisms. Nat Rev Neurol 12:135–149. https://doi.org/10.1038/nrneurol.2016.10 CrossRefPubMed

10.

Rance G, Starr A (2015) Pathophysiological mechanisms and functional hearing consequences of auditory neuropathy. Brain 138:3141–3158. https://doi.org/10.1093/brain/awv270 CrossRefPubMed

11.

Roche JP, Huang BY, Castillo M et al (2010) Imaging characteristics of children with auditory neuropathy spectrum disorder. Otol Neurotol 31:780–788. https://doi.org/10.1097/MAO.0b013e3181d8d528 CrossRefPubMedPubMedCentral

12.

Liu C, Bu X, Wu F, Xing G (2012) Unilateral auditory neuropathy caused by cochlear nerve deficiency. Int J Otolaryngol 2012:914–986. https://doi.org/10.1155/2012/914986 CrossRef

13.

Buchman CA, Roush PA, Teagle HFB et al (2006) Auditory neuropathy characteristics in children with cochlear nerve deficiency. Ear Hear 27:399–408. https://doi.org/10.1097/01.aud.0000224100.30525.ab CrossRefPubMed

14.

Narne VK, Vanaja CS (2008) Speech identification and cortical potentials in individuals with auditory neuropathy. Behav Brain Funct 4:2–9. https://doi.org/10.1186/1744-9081-4-15 CrossRef

15.

Kraus N, Bradlow A, Cheatham M et al (2000) Consequences of neural asynchrony: a case of auditory neuropathy. JARO 1:33–45. https://doi.org/10.1007/s101620010004 CrossRefPubMed

16.

Kumar UA, Jayaram M (2005) Auditory processing in individuals with auditory neuropathy. Behav Brain Funct 1:21. https://doi.org/10.1186/1744-9081-1-21 CrossRefPubMedPubMedCentral

17.

Abdeltawwab M (2014) Auditory N1–P2 cortical event related potentials in auditory neuropathy spectrum disorder patients. J Int Adv Otol 10:270–274. https://doi.org/10.5152/iao.2014.104 CrossRef

18.

Apeksha K, Kumar AU (2018) Cortical processing of speech in individuals with auditory neuropathy spectrum disorder. Eur Arch Otorhinolaryngol 275:1409–1418. https://doi.org/10.1007/s00405-018-4966-8 CrossRefPubMed

19.

Apeksha K, Kumar AU (2017) P300 in individuals with auditory neuropathy spectrum disorder. J Indian Speech Lang Hear Assoc 31:23–28. https://doi.org/10.4103/jisha.JISHA CrossRef

20.

Tremblay KL, Kraus N (2002) Auditory training induces asymmetrical changes in cortical neural activity. J Speech Lang Hear Res 45:564–572. https://doi.org/10.1044/1092-4388(2002/045) CrossRef

21.

Starr A, Sininger YS, Pratt H (2000) The varieties of auditory neuropathy. J Basic Clin Physiol Pharmacol 11:215–230. https://doi.org/10.1515/jbcpp.2000.11.3.215 CrossRefPubMed

22.

Venkatesan S (2009) Ethical guidelines for bio-behavioral research involving human subjects. All India Institute of Speech and Hearing, Mysore

23.

Narne VK, Vanaja CS (2008) Effect of envelope enhancement on speech perception in individuals with auditory neuropathy. Ear Hear 29:45–53. https://doi.org/10.1097/aud.0b013e31812f719a CrossRefPubMed

24.

Duncan C, Barry R, Connolly J et al (2009) Event-related potentials in clinical research: guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400. Clin Neurophysiol 120:1883–1908. https://doi.org/10.1016/j.clinph.2009.07.045 CrossRef

25.

Shelton J, Kumar GP (2010) Comparison between auditory and visual simple reaction times. Neurosci Med 01:30–32. https://doi.org/10.4236/nm.2010.11004 CrossRef

26.

Woods DL, Wyma JM, Yund EW et al (2015) Factors influencing the latency of simple reaction time. Front Hum Neurosci 9:1–12. https://doi.org/10.3389/fnhum.2015.00131 CrossRef

27.

Oates PA, Kurtzberg D, Stapells DR (2002) Effects of sensorineural hearing loss on cortical event-related potential and behavioral measures of speech-sound processing. Ear Hear 23:399–415. https://doi.org/10.1097/01.AUD.0000034777.12562.31 CrossRefPubMed

28.

Murray MM, Michel CM, Grave de Peralta R et al (2004) Rapid discrimination of visual and multisensory memories revealed by electrical neuroimaging. Neuroimage 21:125–135. https://doi.org/10.1016/j.neuroimage.2003.09.035 CrossRefPubMed

29.

De Santis L, Clarke S, Murray M (2007) Automatic and intrinsic auditory “what” and “where” processing in humans revealed by electrical neuroimaging. Cereb Cortex 17:9–17. https://doi.org/10.1093/cercor/bhj119 CrossRefPubMed

30.

Spierer L, Tardif E, Sperdin H et al (2007) Learning-induced plasticity in auditory spatial representations revealed by electrical neuroimaging. J Neurosci 27:5474–5483. https://doi.org/10.1523/JNEUROSCI.0764-07.2007 CrossRefPubMed

31.

Apeksha K, Kumar AU (2017) Speech perception in quiet and in noise condition in individuals with auditory neuropathy spectrum disorder. J Int Adv Otol 13:83–87. https://doi.org/10.5152/iao.2017.3172 CrossRefPubMed

32.

Rance G, McKay C, Grayden D (2004) Perceptual characterization of children with auditory neuropathy. Ear Hear 25:34–46. https://doi.org/10.1097/01.AUD.0000111259.59690.B8 CrossRefPubMed

33.

Kumar UA, Jayaram M (2011) Speech perception in individuals with auditory dys-synchrony. J Laryngol Otol 125:236–245. https://doi.org/10.1017/S0022215113001278 CrossRefPubMed

34.

Zeng F, Kong Y, Michalewski H, Starr A (2005) Perceptual consequences of disrupted auditory nerve activity. J Neurophysiol 93:3050–3063. https://doi.org/10.1152/jn.00985.2004 CrossRefPubMed

35.

Greenberg S (1995) Auditory processing of speech. In: Lass N (ed) Principles of experimental phonetics. Mosby, St. Louis, pp 362–407

36.

Kutas M, Dale A (1997) Electrical and magnetic readings of mental functions. Cognitive neuroscience. MIT Press, Cambridge, pp 197–237

37.

Donchin E, Coles M (1988) Is the P300 component a manifestation of context updating? Behav Brain Sci 11:355–425. https://doi.org/10.1017/S0140525X00058027 CrossRef

Title: Effect of acoustic features on discrimination ability in individuals with auditory neuropathy spectrum disorder: an electrophysiological and behavioral study
Authors: Kumari Apeksha
U. Ajith Kumar
Publication date: 01-06-2019
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 6/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-019-05405-9

ACC 2024 Congress

Springer Medicine

Effect of acoustic features on discrimination ability in individuals with auditory neuropathy spectrum disorder: an electrophysiological and behavioral study

Abstract

Purpose

Methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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