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Published in: European Archives of Oto-Rhino-Laryngology 4/2019

01-04-2019 | Facial Palsy | Otology

Comparative prognosis in patients with Ramsay-Hunt syndrome and Bell’s palsy

Authors: Seok Hyun Kim, Junyang Jung, Su Young Jung, Sung Hwa Dong, Jae Yong Byun, Moon Suh Park, Sang Hoon Kim, Seung Geun Yeo

Published in: European Archives of Oto-Rhino-Laryngology | Issue 4/2019

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Abstract

Purpose

Patients with Ramsay-Hunt syndrome have a poorer prognosis than patients with Bell’s palsy. Factors of metabolic syndrome affecting prognosis were therefore compared between patients with Ramsay-Hunt syndrome and those with Bell’s palsy.

Methods

This retrospective study included 106 with Ramsay-Hunt syndrome and 182 with Bell’s palsy. Age, sex, body mass index, blood pressure, blood test results, and ENoG results, stratified by House–Brackmann grade, were compared in patients with Ramsay-Hunt syndrome and Bell’s palsy. Both groups of patients were treated with steroids and the antiviral agent famciclovir.

Results

Age, sex, body mass index, dyslipidemia, triglyceride, diabetes, hypertension, and onset of palsy did not differ in patients with Ramsay-Hunt syndrome and Bell’s palsy. Rates of favorable recovery in patients with severe facial palsy and DM were lower in patients with Ramsay-Hunt syndrome than with Bell’s palsy and were also lower in low-weight, normal weight, and overweight patients with Ramsay-Hunt syndrome than with Bell’s palsy. Rates of favorable recovery in patients with severe facial palsy and normal HDL, as well as in patients with severe facial palsy and < 10% ENoG, were lower in patients with Ramsay-Hunt syndrome than with Bell’s palsy.

Conclusions

Among patients with severe facial palsy, along with diabetes and < 10% ENoG, unfavorable recovery rates were significantly higher in those with Ramsay-Hunt syndrome than with Bell’s palsy.
Literature
2.
go back to reference Adour KK, Wingerd J, Doty HE (1975) Prevalence of concurrent diabetes mellitus and idiopathic facial paralysis (Bell’s palsy). Diabetes 24:449–451CrossRefPubMed Adour KK, Wingerd J, Doty HE (1975) Prevalence of concurrent diabetes mellitus and idiopathic facial paralysis (Bell’s palsy). Diabetes 24:449–451CrossRefPubMed
3.
go back to reference Sullivan FM, Swan IR, Donnan PT, Morrison JM, Smith BH, McKinstry B, Davenport RJ, Vale LD, Clarkson JE, Hammersley V (2007) Early treatment with prednisolone or acyclovir in Bell’s palsy. N Engl J Med 357:1598–1607CrossRefPubMed Sullivan FM, Swan IR, Donnan PT, Morrison JM, Smith BH, McKinstry B, Davenport RJ, Vale LD, Clarkson JE, Hammersley V (2007) Early treatment with prednisolone or acyclovir in Bell’s palsy. N Engl J Med 357:1598–1607CrossRefPubMed
4.
go back to reference Flint PW, Haughey BH, Robbins KT, Thomas JR, Niparko JK, Lund VJ, Lesperance MM (2014) Cummings Otolaryngology-Head and Neck Surgery 6th edn. Saunders Flint PW, Haughey BH, Robbins KT, Thomas JR, Niparko JK, Lund VJ, Lesperance MM (2014) Cummings Otolaryngology-Head and Neck Surgery 6th edn. Saunders
5.
go back to reference Hunt JR (1968) On herpetic inflammations of the geniculate ganglion. A new syndrome and its complications. Arch Neurol Chic 18:584–589CrossRef Hunt JR (1968) On herpetic inflammations of the geniculate ganglion. A new syndrome and its complications. Arch Neurol Chic 18:584–589CrossRef
6.
go back to reference Ragozzino M, Kurland L, Chu C, Perry H (1988) Population-based study of herpes zoster and its sequelae. Medicine 61:310–316CrossRef Ragozzino M, Kurland L, Chu C, Perry H (1988) Population-based study of herpes zoster and its sequelae. Medicine 61:310–316CrossRef
7.
go back to reference Devriese P, Moesker W (1988) The natural history of facial paralysis in herpes zoster. Clin Otolaryngol 13:289–298CrossRefPubMed Devriese P, Moesker W (1988) The natural history of facial paralysis in herpes zoster. Clin Otolaryngol 13:289–298CrossRefPubMed
8.
go back to reference Adour KK (1994) Otological complications of herpes zoster. Ann neurol 35:62–64CrossRef Adour KK (1994) Otological complications of herpes zoster. Ann neurol 35:62–64CrossRef
9.
go back to reference Byl FM, Adour KK (1977) Auditory symptoms associated with herpes zoster or idiopathic facial paralysis. Laryngoscope 87:372–379CrossRefPubMed Byl FM, Adour KK (1977) Auditory symptoms associated with herpes zoster or idiopathic facial paralysis. Laryngoscope 87:372–379CrossRefPubMed
10.
go back to reference Yeo SW, Lee DH, Jun BC, Chang KH, Park YS (2007) Analysis of prognostic factors in Bell’s palsy and Ramsay Hunt syndrome. Auris Nasus Larynx 34:159–164CrossRefPubMed Yeo SW, Lee DH, Jun BC, Chang KH, Park YS (2007) Analysis of prognostic factors in Bell’s palsy and Ramsay Hunt syndrome. Auris Nasus Larynx 34:159–164CrossRefPubMed
11.
go back to reference Jung SY, Jung J, Byun JY, Park MS, Kim SH, Yeo SG (2018) The effect of metabolic syndrome on Bell’s palsy recovery rate. Acta Oto Laryngol 138:670–674CrossRef Jung SY, Jung J, Byun JY, Park MS, Kim SH, Yeo SG (2018) The effect of metabolic syndrome on Bell’s palsy recovery rate. Acta Oto Laryngol 138:670–674CrossRef
12.
go back to reference Zimmet P, Alberti KGM, Kaufman F, Tajima N, Silink M, Arslanian S, Wong G, Bennett P, Shaw J, Caprio S (2007) The metabolic syndrome in children and adolescents—an IDF consensus report. Pediatr Diabetes 8:299–306CrossRefPubMed Zimmet P, Alberti KGM, Kaufman F, Tajima N, Silink M, Arslanian S, Wong G, Bennett P, Shaw J, Caprio S (2007) The metabolic syndrome in children and adolescents—an IDF consensus report. Pediatr Diabetes 8:299–306CrossRefPubMed
13.
go back to reference Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC (2005) Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 112:2735–2752CrossRef Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC (2005) Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 112:2735–2752CrossRef
14.
go back to reference Ford ES, Giles WH, Dietz WH (2002) Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 287:356–359CrossRefPubMed Ford ES, Giles WH, Dietz WH (2002) Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 287:356–359CrossRefPubMed
15.
go back to reference Kang H, Jung S, Byun J, Park M, Yeo S (2015) Steroid plus antiviral treatment for Bell’s palsy. J Intern Med 277:532–539CrossRefPubMed Kang H, Jung S, Byun J, Park M, Yeo S (2015) Steroid plus antiviral treatment for Bell’s palsy. J Intern Med 277:532–539CrossRefPubMed
16.
go back to reference Lee HY, Byun JY, Park MS, Yeo SG (2013) Steroid-antiviral treatment improves the recovery rate in patients with severe Bell’s palsy. Am J Med 12:336–341CrossRef Lee HY, Byun JY, Park MS, Yeo SG (2013) Steroid-antiviral treatment improves the recovery rate in patients with severe Bell’s palsy. Am J Med 12:336–341CrossRef
17.
18.
go back to reference Meier JL, Straus SE (1992) Comparative biology of latent varicella-zoster virus and herpes simplex virus infections. J Infect Dis 166:13–23CrossRef Meier JL, Straus SE (1992) Comparative biology of latent varicella-zoster virus and herpes simplex virus infections. J Infect Dis 166:13–23CrossRef
20.
go back to reference Ikeda M, Abiko Y, Kukimoto N, Omori H, Nakazato H, Ikeda K (2005) Clinical factors that influence the prognosis of facial nerve paralysis and the magnitudes of influence. Laryngoscope 115:855–860CrossRefPubMed Ikeda M, Abiko Y, Kukimoto N, Omori H, Nakazato H, Ikeda K (2005) Clinical factors that influence the prognosis of facial nerve paralysis and the magnitudes of influence. Laryngoscope 115:855–860CrossRefPubMed
21.
go back to reference Katusic SK, Beard CM, Wiederholt W, Bergstralh EJ, Kurland LT (1986) Incidence, clinical features, and prognosis in Bell’s palsy, Rochester, Minnesota, 1968–1982. Ann Neurol 20:622–627CrossRefPubMed Katusic SK, Beard CM, Wiederholt W, Bergstralh EJ, Kurland LT (1986) Incidence, clinical features, and prognosis in Bell’s palsy, Rochester, Minnesota, 1968–1982. Ann Neurol 20:622–627CrossRefPubMed
22.
go back to reference Peitersen E (2002) Bell’s palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Oto Laryngol 122:4–30CrossRef Peitersen E (2002) Bell’s palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Oto Laryngol 122:4–30CrossRef
23.
go back to reference Lee DH, Chae SY, Park YS, Yeo SW (2006) Prognostic value of electroneurography in Bell’s palsy and Ramsay–Hunt’s syndrome. Clin Otolaryngol 31:144–148CrossRefPubMed Lee DH, Chae SY, Park YS, Yeo SW (2006) Prognostic value of electroneurography in Bell’s palsy and Ramsay–Hunt’s syndrome. Clin Otolaryngol 31:144–148CrossRefPubMed
24.
go back to reference Byun H, Cho YS, Jang JY, Chung KW, Hwang S, Chung WH, Hong SH (2013) Value of electroneurography as a prognostic indicator for recovery in acute severe inflammatory facial paralysis: a prospective study of Bell’s palsy and Ramsay-Hunt syndrome. Laryngoscope 123:2526–2532CrossRefPubMed Byun H, Cho YS, Jang JY, Chung KW, Hwang S, Chung WH, Hong SH (2013) Value of electroneurography as a prognostic indicator for recovery in acute severe inflammatory facial paralysis: a prospective study of Bell’s palsy and Ramsay-Hunt syndrome. Laryngoscope 123:2526–2532CrossRefPubMed
Metadata
Title
Comparative prognosis in patients with Ramsay-Hunt syndrome and Bell’s palsy
Authors
Seok Hyun Kim
Junyang Jung
Su Young Jung
Sung Hwa Dong
Jae Yong Byun
Moon Suh Park
Sang Hoon Kim
Seung Geun Yeo
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
European Archives of Oto-Rhino-Laryngology / Issue 4/2019
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-019-05300-3

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