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European Archives of Oto-Rhino-Laryngology

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01-08-2018 | Laryngology

Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma

Authors: Daniel Pedregal-Mallo, Mario Sánchez Canteli, Fernando López, César Álvarez-Marcos, José Luis Llorente, Juan Pablo Rodrigo

Published in: European Archives of Oto-Rhino-Laryngology | Issue 8/2018

Abstract

Introduction

Transoral laser microsurgery (TLM) has become the standard approach for treatment of early-stage laryngeal carcinoma in most institutions due to their good oncological and functional results with few local complications. The purpose of this study was to analyze the oncological and functional results of TLM in the treatment of laryngeal tumors at our Hospital.

Materials and methods

Patients with laryngeal squamous cell carcinoma (LSCC) treated from 1998 to 2013 with TLM with curative intention, and with a minimum follow-up of 24 months, were reviewed.

Results

203 patients with LSCC were included. 195 patients were men (96%) and 8 women (4%), with a mean age of 63 years. The series includes 134 (66%) T1, 40 (20%) T2, and 29 (14%) T3-classified tumors. 116 tumors (57%) were in the glottis, 79 (39%) in the supraglottis and 8 (4%) in the anterior commissure. 16 patients (8%) received adjuvant radiotherapy. Initial local control was obtained in 75.5% of patients. The 5-year overall survival rate was 84% and the 5-year disease-specific survival was 90%. The presence of nodal metastasis (p < 0.001) and the involvement of the surgical margins (p = 0.004) were associated with a lower disease-specific survival in the multivariate analysis. All but three patients with local control of the disease reassumed oral diet, and none were tracheostomy-dependent. The 5-year laryngeal preservation rate was 85%.

Conclusions

TLM is a minimally invasive treatment for early and moderately-advanced laryngeal carcinomas, with good oncologic and functional outcomes, and few complications as well.

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Title: Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma
Authors: Daniel Pedregal-Mallo
Mario Sánchez Canteli
Fernando López
César Álvarez-Marcos
José Luis Llorente
Juan Pablo Rodrigo
Publication date: 01-08-2018
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 8/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-018-5027-z

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Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma

Abstract

Introduction

Materials and methods

Results

Conclusions

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Abstract

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Materials and methods

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Conclusions

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