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European Archives of Oto-Rhino-Laryngology

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01-01-2018 | Head and Neck

Relationship between the severity of laryngopharyngeal reflux and sleep apnea: using drug-induced sleep endoscopy (DISE)

Authors: Joong Seob Lee, Sung Jae Heo, Jung Soo Kim, Dongbin Ahn, Jin Ho Sohn, Heejin Kim

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2018

Abstract

Objectives

The aim of the study is to identify the following associations: (1) severity of obstructive sleep apnea syndrome (OSAS) and laryngopharyngeal reflux (LPR)-related clinical parameters, such as reflux finding score (RFS), reflux symptom index (RSI), and LPR–health-related quality of life (LPR–HRQOL) and (2) complete obstruction on drug-induced sleep endoscopy (DISE) and LPR-related clinical parameters.

Materials and methods

Subjects included the OSAS patients without surgery history and all patients perform the polysomnography (PSG) and DISE for their OSAS. Demographics, polysomnographic data, DISE results, and LPR-related parameters were collected prospectively. The patients were divided into age-, sex-, and BMI-matched two groups, according to numbers of complete obstruction on DISE (complete obstruction at 0–1 subsites (unilevel) vs. 2–4 subsites (multilevel). Finally, 19 patients with unilevel complete obstruction and 38 patients with multilevel complete obstruction were compared. The multiple linear regression analysis was employed to determine the predictors of LPR-related quality of life.

Results

Among 88 patients, 19 patients demonstrated unilevel complete obstruction, and 69 patients demonstrated multilevel complete obstruction on DISE. There were no significant correlation between OSAS severity and RFS, RSI, and scores of LPR–HRQOL. Multilevel complete obstruction on DISE did not affect the LPR-related clinical parameters (p > 0.05). The result of multiple linear regression demonstrated complete obstruction at the epiglottis had a strong influence on the high scores of LPR–HRQOL.

Conclusion

LPR is commonly developing disease with OSAS, but the OSAS severity did not affect the LPR-related parameters. The multilevel complete obstruction on DISE was not associated with the LPR-related clinical parameters.

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Title: Relationship between the severity of laryngopharyngeal reflux and sleep apnea: using drug-induced sleep endoscopy (DISE)
Authors: Joong Seob Lee
Sung Jae Heo
Jung Soo Kim
Dongbin Ahn
Jin Ho Sohn
Heejin Kim
Publication date: 01-01-2018
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 1/2018
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-017-4812-4

ACC 2024 Congress

Springer Medicine

Relationship between the severity of laryngopharyngeal reflux and sleep apnea: using drug-induced sleep endoscopy (DISE)

Abstract

Objectives

Materials and methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusion

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