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European Archives of Oto-Rhino-Laryngology

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01-02-2017 | Head and Neck

MRI of diffuse large B-cell non-Hodgkin’s lymphoma of the head and neck: comparison of Waldeyer’s ring and sinonasal lymphoma

Authors: Ann D. King, Benjamin King Hong Law, Wai Kiu Tang, Frankie Kwok Fai Mo, Radha Raghupathy, Kunwar S. Bhatia, Kenny I. K. Lei

Published in: European Archives of Oto-Rhino-Laryngology | Issue 2/2017

Abstract

To document the magnetic resonance imaging (MRI) features of diffuse large B-cell lymphoma (DLBCL) in Waldeyer’s ring (WR) and the sinonasal (SN) region, and to identify any differences between lymphatic and extra-lymphatic DLBCLs, and predictors of disease beyond the neck. Primary, nodal, and multifocal sites on head and neck MRI were compared between 31 WR and 15 SN DLBCL, and between 27 patients with disease confined to the head and neck and 16 patients with disease beyond the neck, using logistic regression. Compared to SN, WR DLBCLs had significantly smaller primary tumour volumes (p = 0.009), less deep invasion (p = 0.001), and more nodal disease (p = 0.016). Tumour site (WR vs. SN) was an independent predictor of deep invasion (p = 0.007). Nodal and multifocal diseases were predictors of disease beyond the neck (p = 0.027 and 0.011, respectively). Lymphatic WR DLBCLs were less locally aggressive but had greater propensity to nodal spread than extra-lymphatic SN DLBCLs. Nodal and multifocal diseases predicted disease beyond the neck.

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Title: MRI of diffuse large B-cell non-Hodgkin’s lymphoma of the head and neck: comparison of Waldeyer’s ring and sinonasal lymphoma
Authors: Ann D. King
Benjamin King Hong Law
Wai Kiu Tang
Frankie Kwok Fai Mo
Radha Raghupathy
Kunwar S. Bhatia
Kenny I. K. Lei
Publication date: 01-02-2017
Publisher: Springer Berlin Heidelberg
Published in: European Archives of Oto-Rhino-Laryngology / Issue 2/2017
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-016-4337-2

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MRI of diffuse large B-cell non-Hodgkin’s lymphoma of the head and neck: comparison of Waldeyer’s ring and sinonasal lymphoma

Abstract

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Abstract

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