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Archives of Gynecology and Obstetrics

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29-11-2021 | Coronavirus | Review

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Authors: Leila Khedmat, Pegah Mohaghegh, Maryam Veysizadeh, Azadeh Hosseinkhani, Sanaz Fayazi, Monirsadat Mirzadeh

Published in: Archives of Gynecology and Obstetrics | Issue 2/2022

Abstract

Background

The establishment of a risk-appropriate care approach for pregnant women and newborn infants under the COVID-19 pneumonia is vital to prevent the main pregnancy complications.

Objectives and design

This study reviewed the vertical transmission (VT) potential of COVID-19 pneumonia in pregnant women. Key-related symptoms and adverse clinical outcomes for mothers and infants before and after childbirth were summarized. Some practical therapies and preventive health solutions were also proposed.

Results

There was a high susceptibility in pregnant women to COVID-19 infection, especially in the third trimester of pregnancy. The most common symptoms in 22–40-year-old patients infected with COVID-19 were fever (87.6%), cough (52.3%), dyspnea (27.6%), fatigue (22.4%), sore throat (13.5%), malaise (9.4%), and diarrhea (3.4%), respectively. The viral infection led to an increase in preterm labor and cesarean delivery without any intrauterine infection and severe neonatal asphyxia. No infection in the newborn infants was reported despite a high risk of the VT phenomenon. The most important therapies were the reception of antiviral and antibiotic drugs, oxygenation therapy, psychological interventions, and food supplements with health-promoting effects. The best proposed medical strategies to control the COVID-19 infection were bi-monthly screening and following-up the mothers’ and fetuses’ health, not using the potent broad-spectrum antibiotics and corticosteroids, providing the delivery room with negative pressure for emergency cesarean section, and the immediate isolation of newborns after childbirth without direct breastfeeding.

Conclusion

Babies with respiratory problems may be born to some mothers with COVID-19, who have weak immune systems. Thus, the virus transmission cycle should be disrupted to prevent adverse maternal and fetal outcomes by integrating individual health guidelines, efficient medical care therapies, and hospital preventive practices.

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Title: Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments
Authors: Leila Khedmat
Pegah Mohaghegh
Maryam Veysizadeh
Azadeh Hosseinkhani
Sanaz Fayazi
Monirsadat Mirzadeh
Publication date: 29-11-2021
Publisher: Springer Berlin Heidelberg
Keywords: Coronavirus
Computed Tomography
Computed Tomography
Pneumonia
COVID-19
Published in: Archives of Gynecology and Obstetrics / Issue 2/2022
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-021-06325-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Pregnant women and infants against the infection risk of COVID-19: a review of prenatal and postnatal symptoms, clinical diagnosis, adverse maternal and neonatal outcomes, and available treatments

Abstract

Background

Objectives and design

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objectives and design

Results

Conclusion

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