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01-05-2015 | Reply

Authors’ reply to: “Empiric” inositol supplementation in normal-weight non-insulin resistant women with polycystic ovarian disease: from the absence of benefit to the potential adverse effects

Authors: Antonio Simone Laganà, Alfonsa Pizzo

Published in: Archives of Gynecology and Obstetrics | Issue 5/2015

Excerpt

Dear Editor, …

Laganà AS, Barbaro L, Pizzo A (2014) Evaluation of ovarian function and metabolic factors in women affected by polycystic ovary syndrome after treatment with d-chiro-inositol. Arch Gynecol Obstet. doi:10.1007/s00404-014-3552-6

Vitagliano A, QuarantaM Noventa M, Gizzo S (2015) “Empiric” inositol supplementation in normal-weight non insulin resistant women with polycystic ovarian disease: from the absence of benefit to the potential adverse effects. Arch Gynecol Obstet. doi:10.1007/s00404-015-3662-9 PubMed

Unfer V, Carlomagno G, Dante G, Facchinetti F (2012) Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials. Gynecol Endocrinol 28:509–515CrossRefPubMed

Galazis N, Galazi M, Atiomo W (2011) d-Chiro-inositol and its significance in polycystic ovary syndrome: a systematic review. Gynecol Endocrinol 27:256–262CrossRefPubMed

Genazzani AD, Santagni S, Rattighieri E, Chierchia E, Despini G, Marini G, Prati A, Simoncini T (2014) Modulatory role of d-chiro-inositol (DCI) on LH and insulin secretion in obese PCOS patients. Gynecol Endocrinol 30:438–443CrossRefPubMed

Baptiste CG, Battista MC, Trottier A, Baillargeon JP (2010) Insulin and hyperandrogenism in women with polycystic ovary syndrome. J Steroid Biochem Mol Biol 122:42–52CrossRefPubMed

Cheang KI, Baillargeon JP, Essah PA, Ostlund RE Jr, Apridonize T, Islam L, Nestler JE (2008) Insulin-stimulated release of d-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome. Metabolism 57:1390–1397CrossRefPubMedCentralPubMed

Isabella R, Raffone E (2012) Does ovary need d-chiro-inositol? J Ovarian Res 5:14CrossRefPubMedCentralPubMed

Pizzo A, Laganà AS, Barbaro L (2014) Comparison between effects of myo-inositol and d-chiro-inositol on ovarian function and metabolic factors in women with PCOS. Gynecol Endocrinol 30:205–208CrossRefPubMed

10.

Laganà AS, Pizzo A (2013) Know your enemy: the rationale of using inositol in the treatment of polycystic ovary syndrome. Endocrinol Metab Syndr 2:e121

11.

Vitagliano A, Noventa M, Gizzo S (2014) Is it time to consider patients suffering from endometriosis-related infertility as “novel candidates” for targeted peri-conceptional d-chiro inositol supplementation? Hypothesis, rationale and some considerations. J Assist Reprod Genet. doi:10.1007/s10815-014-0412-z PubMed

12.

Gizzo S, Capuzzo D, Zicchina C, Di Gangi S, Coronella ML, Andrisani A, Gangemi M, Nardelli GB (2014) Could empirical low-dose-aspirin administration during IVF cycle affect both the oocytes and embryos quality via COX 1–2 activity inhibition? J Assist Reprod Genet 31:261–268CrossRefPubMedCentralPubMed

Title: Authors’ reply to: “Empiric” inositol supplementation in normal-weight non-insulin resistant women with polycystic ovarian disease: from the absence of benefit to the potential adverse effects
Authors: Antonio Simone Laganà
Alfonsa Pizzo
Publication date: 01-05-2015
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 5/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-015-3663-8

Keynote webinar | Spotlight on medication adherence

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Authors’ reply to: “Empiric” inositol supplementation in normal-weight non-insulin resistant women with polycystic ovarian disease: from the absence of benefit to the potential adverse effects

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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“Empiric” inositol supplementation in normal-weight non insulin resistant women with polycystic ovarian disease: from the absence of benefit to the potential adverse effects