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Archives of Gynecology and Obstetrics

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01-06-2014 | General Gynecology

Differences in the clinical phenotype of adenomyosis and leiomyomas: a retrospective, questionnaire-based study

Authors: Bettina Boeer, Markus Wallwiener, Joachim Rom, Birgitt Schoenfisch, Sara Y. Brucker, Florin A. Taran

Published in: Archives of Gynecology and Obstetrics | Issue 6/2014

Abstract

Purpose

To compare women undergoing laparoscopic hysterectomy with adenomyosis and women with leiomyomas.

Materials and methods

Retrospective and questionnaire-based study was conducted at the Department of Obstetrics and Gynecology, University Women’s Clinic, Tuebingen, Germany. The study sample comprised a total of 454 women who underwent hysterectomy for adenomyosis or leiomyomas and responded to the questionnaire; 52 (11.4 %) women with a histologic diagnosis of adenomyosis and 452 (88.6 %) women with a histologic diagnosis of leiomyomas.

Results

Both groups of patients had enlarged uteri, but women with adenomyosis had a lower mean uterine weight as compared to women with leiomyomas (p < 0.001). Women with adenomyosis had significantly more pregnancies (p = 0.003), were more likely to have more than one pregnancy (p = 0.033) or more than one delivery (p = 0.025) as compared to women with leiomyomas. In addition, women with adenomyosis had a significantly higher surgical procedure score (p = 0.017), had more frequently a history of laparotomy (p = 0.042) and a history of Cesarean section as compared to women with leiomyomas only (p = 0.024). Significantly, more women with adenomyosis had pelvic pain or pressure as compared to women with leiomyomas (p = 0.045). We observed no differences between the two groups of patients regarding pelvic pain during the menstrual period, irregular menstrual periods, heavy bleeding, painful sexual intercourse and urination problems. Furthermore, we observed no differences in the therapeutic impact of the surgical procedure between the two patient groups.

Conclusions

Women with a histologic diagnosis of adenomyosis differ from women who have only leiomyomas at the time of hysterectomy.

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Title: Differences in the clinical phenotype of adenomyosis and leiomyomas: a retrospective, questionnaire-based study
Authors: Bettina Boeer
Markus Wallwiener
Joachim Rom
Birgitt Schoenfisch
Sara Y. Brucker
Florin A. Taran
Publication date: 01-06-2014
Publisher: Springer Berlin Heidelberg
Published in: Archives of Gynecology and Obstetrics / Issue 6/2014
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-013-3141-0

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Differences in the clinical phenotype of adenomyosis and leiomyomas: a retrospective, questionnaire-based study

Abstract

Purpose

Materials and methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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