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Published in: Archives of Orthopaedic and Trauma Surgery 6/2019

01-06-2019 | Magnetic Resonance Imaging | Arthroscopy and Sports Medicine

No added value using SPECT/CT to analyze persistent symptoms after anterior cruciate ligament reconstruction

Authors: Christian Egloff, Lukas Huber, Markus Wurm, Geert Pagenstert

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 6/2019

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Abstract

Purpose

To evaluate the diagnostic and clinical value of SPECT/CT compared to the standard algorithm for patients with persistent symptoms after anterior cruciate ligament reconstructions. The standard algorithm uses clinical information, conventional radiographs, MRI and CT scan, while the trial algorithm uses the same information but SPECT/CT in addition.

Methods

In a diagnostic comparative trial three experienced surgeons evaluated 23 consecutive patients with persistent symptoms after ACL reconstruction using first standard and second the trial algorithm with a time interval. Each rater had to establish a diagnosis and therapeutic decision with each algorithm. On MRI, graft continuity, bone marrow edema, chondral and meniscal lesions, femoral notch osteophytes were evaluated. Bone tracer uptake in SPECT/CT was anatomically analyzed and compared with MRI findings. MRI findings and SPECT/CT tracer uptake were correlated using Spearman’s rho test.

Results

Additional SPECT/CT analysis did not change diagnosis in any case and did not correlate with clinical graft integrity. Treatment decisions remained unchanged as well. Chondral lesions, arthritic changes, meniscal lesions, graft impingement are best visualized in MRI and showed correspondent tracer uptake in SPECT/CT. Tunnel position was well classified with standard CT scan and showed no correlation with SPECT/CT tracer uptake.

Conclusion

Information derived by SPECT/CT in addition to the standard algorithm using clinical information, X-rays, MRI, and CT scan did not change the diagnosis or treatment plan. There is currently no justification to implement SPECT/CT for patients with persistent symptoms after anterior cruciate ligament reconstructions.

Level of evidence

Level II: diagnostic comparative study.
Literature
4.
go back to reference Trojani C, Sbihi A, Djian P, Potel JF, Hulet C, Jouve F, Bussiere C, Ehkirch FP, Burdin G, Dubrana F, Beaufils P, Franceschi JP, Chassaing V, Colombet P, Neyret P (2011) Causes for failure of ACL reconstruction and influence of meniscectomies after revision. Knee Surg Sports Traumatol Arthrosc 19(2):196–201. https://doi.org/10.1007/s00167-010-1201-6 CrossRef Trojani C, Sbihi A, Djian P, Potel JF, Hulet C, Jouve F, Bussiere C, Ehkirch FP, Burdin G, Dubrana F, Beaufils P, Franceschi JP, Chassaing V, Colombet P, Neyret P (2011) Causes for failure of ACL reconstruction and influence of meniscectomies after revision. Knee Surg Sports Traumatol Arthrosc 19(2):196–201. https://​doi.​org/​10.​1007/​s00167-010-1201-6 CrossRef
6.
go back to reference Araki D, Kuroda R, Matsumoto T, Nagamune K, Matsushita T, Hoshino Y, Oka S, Nishizawa Y, Kurosaka M (2014) Three-dimensional analysis of bone tunnel changes after anatomic double-bundle anterior cruciate ligament reconstruction using multidetector-row computed tomography. Am J Sports Med 42(9):2234–2241. https://doi.org/10.1177/0363546514540274 CrossRefPubMed Araki D, Kuroda R, Matsumoto T, Nagamune K, Matsushita T, Hoshino Y, Oka S, Nishizawa Y, Kurosaka M (2014) Three-dimensional analysis of bone tunnel changes after anatomic double-bundle anterior cruciate ligament reconstruction using multidetector-row computed tomography. Am J Sports Med 42(9):2234–2241. https://​doi.​org/​10.​1177/​0363546514540274​ CrossRefPubMed
8.
go back to reference Marchant MH Jr, Willimon SC, Vinson E, Pietrobon R, Garrett WE, Higgins LD (2010) Comparison of plain radiography, computed tomography, and magnetic resonance imaging in the evaluation of bone tunnel widening after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 18(8):1059–1064. https://doi.org/10.1007/s00167-009-0952-4 CrossRef Marchant MH Jr, Willimon SC, Vinson E, Pietrobon R, Garrett WE, Higgins LD (2010) Comparison of plain radiography, computed tomography, and magnetic resonance imaging in the evaluation of bone tunnel widening after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 18(8):1059–1064. https://​doi.​org/​10.​1007/​s00167-009-0952-4 CrossRef
10.
go back to reference Biercevicz AM, Akelman MR, Fadale PD, Hulstyn MJ, Shalvoy RM, Badger GJ, Tung GA, Oksendahl HL, Fleming BC (2015) MRI volume and signal intensity of ACL graft predict clinical, functional, and patient-oriented outcome measures after ACL reconstruction. Am J Sports Med 43(3):693–699. https://doi.org/10.1177/0363546514561435 CrossRef Biercevicz AM, Akelman MR, Fadale PD, Hulstyn MJ, Shalvoy RM, Badger GJ, Tung GA, Oksendahl HL, Fleming BC (2015) MRI volume and signal intensity of ACL graft predict clinical, functional, and patient-oriented outcome measures after ACL reconstruction. Am J Sports Med 43(3):693–699. https://​doi.​org/​10.​1177/​0363546514561435​ CrossRef
12.
go back to reference Hirschmann MT, Mathis D, Afifi FK, Rasch H, Henckel J, Amsler F, Wagner CR, Friederich NF, Arnold MP (2013) Single photon emission computerized tomography and conventional computerized tomography (SPECT/CT) for evaluation of patients after anterior cruciate ligament reconstruction: a novel standardized algorithm combining mechanical and metabolic information. Knee Surg Sports Traumatol Arthrosc 21(4):965–974. https://doi.org/10.1007/s00167-012-2083-6 CrossRef Hirschmann MT, Mathis D, Afifi FK, Rasch H, Henckel J, Amsler F, Wagner CR, Friederich NF, Arnold MP (2013) Single photon emission computerized tomography and conventional computerized tomography (SPECT/CT) for evaluation of patients after anterior cruciate ligament reconstruction: a novel standardized algorithm combining mechanical and metabolic information. Knee Surg Sports Traumatol Arthrosc 21(4):965–974. https://​doi.​org/​10.​1007/​s00167-012-2083-6 CrossRef
14.
go back to reference Ryan PJ, Reddy K, Fleetcroft J (1998) A prospective comparison of clinical examination, MRI, bone SPECT, and arthroscopy to detect meniscal tears. Clin Nucl Med 23(12):803–806CrossRefPubMed Ryan PJ, Reddy K, Fleetcroft J (1998) A prospective comparison of clinical examination, MRI, bone SPECT, and arthroscopy to detect meniscal tears. Clin Nucl Med 23(12):803–806CrossRefPubMed
20.
go back to reference Duc SR, Zanetti M, Kramer J, Kach KP, Zollikofer CL, Wentz KU (2005) Magnetic resonance imaging of anterior cruciate ligament tears: evaluation of standard orthogonal and tailored paracoronal images. Acta Radiol 46(7):729–733CrossRefPubMed Duc SR, Zanetti M, Kramer J, Kach KP, Zollikofer CL, Wentz KU (2005) Magnetic resonance imaging of anterior cruciate ligament tears: evaluation of standard orthogonal and tailored paracoronal images. Acta Radiol 46(7):729–733CrossRefPubMed
21.
go back to reference Speer KP, Spritzer CE, Bassett FH III, Feagin JA Jr, Garrett WE Jr (1992) Osseous injury associated with acute tears of the anterior cruciate ligament. Am J Sports Med 20(4):382–389CrossRef Speer KP, Spritzer CE, Bassett FH III, Feagin JA Jr, Garrett WE Jr (1992) Osseous injury associated with acute tears of the anterior cruciate ligament. Am J Sports Med 20(4):382–389CrossRef
22.
go back to reference Mainil-Varlet P, Aigner T, Brittberg M, Bullough P, Hollander A, Hunziker E, Kandel R, Nehrer S, Pritzker K, Roberts S, Stauffer E, International Cartilage Repair S (2003) Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS). J Bone Jt Surg Am 85-A(Suppl 2):45–57CrossRef Mainil-Varlet P, Aigner T, Brittberg M, Bullough P, Hollander A, Hunziker E, Kandel R, Nehrer S, Pritzker K, Roberts S, Stauffer E, International Cartilage Repair S (2003) Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS). J Bone Jt Surg Am 85-A(Suppl 2):45–57CrossRef
23.
go back to reference Bernard M, Hertel P, Hornung H, Cierpinski T (1997) Femoral insertion of the ACL. Radiographic quadrant method. Am J Knee Surg 10(1):14–21 (discussion 21-12) Bernard M, Hertel P, Hornung H, Cierpinski T (1997) Femoral insertion of the ACL. Radiographic quadrant method. Am J Knee Surg 10(1):14–21 (discussion 21-12)
26.
go back to reference Amis AA, Beynnon B, Blankevoort L, Chambat P, Christel P, Durselen L, Friederich N, Grood E, Hertel P, Jakob R et al (1994) Proceedings of the ESSKA scientific workshop on reconstruction of the anterior and posterior cruciate ligaments. Knee Surg Sports Traumatol Arthrosc 2(3):124–132CrossRefPubMed Amis AA, Beynnon B, Blankevoort L, Chambat P, Christel P, Durselen L, Friederich N, Grood E, Hertel P, Jakob R et al (1994) Proceedings of the ESSKA scientific workshop on reconstruction of the anterior and posterior cruciate ligaments. Knee Surg Sports Traumatol Arthrosc 2(3):124–132CrossRefPubMed
28.
go back to reference Staubli HU, Rauschning W (1994) Tibial attachment area of the anterior cruciate ligament in the extended knee position. Anatomy and cryosections in vitro complemented by magnetic resonance arthrography in vivo. Knee Surg Sports Traumatol Arthrosc 2(3):138–146CrossRefPubMed Staubli HU, Rauschning W (1994) Tibial attachment area of the anterior cruciate ligament in the extended knee position. Anatomy and cryosections in vitro complemented by magnetic resonance arthrography in vivo. Knee Surg Sports Traumatol Arthrosc 2(3):138–146CrossRefPubMed
29.
go back to reference O’Duffy EK, Clunie GP, Gacinovic S, Edwards JC, Bomanji JB, Ell PJ (1998) Foot pain: specific indications for scintigraphy. Br J Rheumatol 37(4):442–447CrossRefPubMed O’Duffy EK, Clunie GP, Gacinovic S, Edwards JC, Bomanji JB, Ell PJ (1998) Foot pain: specific indications for scintigraphy. Br J Rheumatol 37(4):442–447CrossRefPubMed
30.
go back to reference Cronbach L (1951) Coefficient alpha as a measure of test score. Psychometrika 16:297–334CrossRef Cronbach L (1951) Coefficient alpha as a measure of test score. Psychometrika 16:297–334CrossRef
33.
go back to reference Mathis DT, Hirschmann A, Falkowski AL, Kiekara T, Amsler F, Rasch H, Hirschmann MT (2018) Increased bone tracer uptake in symptomatic patients with ACL graft insufficiency: a correlation of MRI and SPECT/CT findings. Knee Surg Sports Traumatol Arthrosc 26(2):563–573. https://doi.org/10.1007/s00167-017-4588-5 CrossRef Mathis DT, Hirschmann A, Falkowski AL, Kiekara T, Amsler F, Rasch H, Hirschmann MT (2018) Increased bone tracer uptake in symptomatic patients with ACL graft insufficiency: a correlation of MRI and SPECT/CT findings. Knee Surg Sports Traumatol Arthrosc 26(2):563–573. https://​doi.​org/​10.​1007/​s00167-017-4588-5 CrossRef
Metadata
Title
No added value using SPECT/CT to analyze persistent symptoms after anterior cruciate ligament reconstruction
Authors
Christian Egloff
Lukas Huber
Markus Wurm
Geert Pagenstert
Publication date
01-06-2019
Publisher
Springer Berlin Heidelberg
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 6/2019
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-019-03117-7

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