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Archives of Orthopaedic and Trauma Surgery

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01-08-2012 | Knee Arthroplasty

Fibrin sealants in orthopaedic surgery: practical experiences derived from use of QUIXIL^® in total knee arthroplasty

Authors: Torsten Kluba, Katrin Fiedler, Beate Kunze, Ingmar Ipach, Andreas Suckel

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 8/2012

Abstract

Background

Total knee arthroplasty is associated with a significant postoperative blood loss even without any form of perioperative anticoagulation.

Methods

The potential role of QUIXIL^®, a fibrin sealant used in orthopaedic surgery to control blood loss and avoid blood transfusions in patients undergoing total knee arthroplasty was evaluated in a prospective randomized trial with twenty-four patients diagnosed with primary osteoarthritis of the knee.

Results

Results showed that application of 2 ml QUIXIL^® adds costs to treatment without reducing the number of transfused red blood cell counts and postoperative haemoglobin loss. However, significant lower levels of postoperative fluid loss (P = 0.026) was detected in QUIXIL^® treated patients.

Conclusion

Regarding cost effectiveness and benefit no indication for the use of 2 ml QUIXIL^® fibrin sealant in standard knee arthroplasty could be proofed statistically.

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Title: Fibrin sealants in orthopaedic surgery: practical experiences derived from use of QUIXIL® in total knee arthroplasty
Authors: Torsten Kluba
Katrin Fiedler
Beate Kunze
Ingmar Ipach
Andreas Suckel
Publication date: 01-08-2012
Publisher: Springer-Verlag
Published in: Archives of Orthopaedic and Trauma Surgery / Issue 8/2012
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-012-1519-2

At a glance: The STEP trials

Springer Medicine

Fibrin sealants in orthopaedic surgery: practical experiences derived from use of QUIXIL^® in total knee arthroplasty

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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