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Published in: Archives of Orthopaedic and Trauma Surgery 6/2010

01-06-2010 | Osteoporotic Fracture Management

Indications and contraindications for vertebroplasty and kyphoplasty

Authors: Marc Röllinghoff, Kourosh Zarghooni, Klaus Schlüter-Brust, Rolf Sobottke, Ulf Schlegel, Peer Eysel, Karl-Stefan Delank

Published in: Archives of Orthopaedic and Trauma Surgery | Issue 6/2010

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Abstract

Introduction

Vertebral fractures (VF) are a leading cause of morbidity in the elderly. In the past decade, minimally invasive bone augmentation techniques for VF, such as percutaneous vertebroplasty (VP) and kyphoplasty (KP) have become more widespread. According to the literature, both techniques provide significant pain relief. However, KP is more expensive and technically more demanding than VP. The current study surveyed German surgeons who practice percutaneous augmentation to evaluate and compare decisions regarding the implementation of these techniques. Is there a difference in the indications and contraindications of VP and KP compared with the interdisciplinary consensus paper on VP and KP of the German medical association in the treatment of VF?

Methods

A multiple choice questionnaire was designed with questions regarding diagnostic procedures, clinical and radiologic (AO classification) indications, as well as contraindications for both VP and KP. A panel of five experts refined the initial questionnaire. The final version was then sent to 580 clinics registered to practice KP in Germany. The statistical analysis was done by two authors, who collected the questionnaire data and Wilcoxon’s signed ranks test was performed for non-parametric variables with SPSS.

Results

327 of 580 questionnaires (56.4%) were completed and returned. 151 (46.2%) of participants were performing both procedures, and 176 (53.8%) performed KP only. Median duration from onset of acute pain to intervention was 3 weeks. For most participants (95.4%), consistent back pain at the fracture level with a visual analog scale score over 5 was the main clinical indication for VP and KP. A1 and A3.1 fractures from osteoporosis and metastasis were considered indications for KP. Osteoporotic A1.1 fractures were an indication for VP. Traumatic A3.2 fractures were not an indication for either procedure. Major contraindications to both procedures were active infection (94.7%), cement allergy (86.8%), and coagulation disorders (80.3%).

Conclusion

Vertebroplasty and kyphoplasty both have roles in the treatment of vertebral fractures. However, we could see differences in the indications for the two percutaneous techniques. Participants of this study found more indications for KP versus VP in cases of painful A1.2 and A3.1 fractures due to osteoporosis, metastasis, and trauma. About half of the respondents reported that VP is indicated for osteoporotic and pathologic A1.1 fractures. This study offers only limited conclusions. Open questionnaires and prospective data from all clinicians performing these procedures should be analyzed to offer more specific information.
Literature
1.
go back to reference Bierschneider M, Sabo D, Meeder PJ (2005) Interdisziplinäres Konsensuspapier zur Vertebroplastie/Kyphoplastie. Fortschr Röntgenstr 177:1590–1592 Bierschneider M, Sabo D, Meeder PJ (2005) Interdisziplinäres Konsensuspapier zur Vertebroplastie/Kyphoplastie. Fortschr Röntgenstr 177:1590–1592
2.
go back to reference Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348:1535–1541CrossRefPubMed Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348:1535–1541CrossRefPubMed
3.
go back to reference Borgström F, Zethraeus N, Johnell O, Lidgren L, Ponzer S, Sevensson O, Abdon P, Ornstein E, Lunsjö K, Thorngren KG, Sernbo I, Rehnberg C, Jönsson B (2006) Costs and quality of life associated with osteoporosis-related fractures in Sweden. Osteoporos Int 17(5):637–650. doi:10.1007/s00198-005-0015-8 CrossRefPubMed Borgström F, Zethraeus N, Johnell O, Lidgren L, Ponzer S, Sevensson O, Abdon P, Ornstein E, Lunsjö K, Thorngren KG, Sernbo I, Rehnberg C, Jönsson B (2006) Costs and quality of life associated with osteoporosis-related fractures in Sweden. Osteoporos Int 17(5):637–650. doi:10.​1007/​s00198-005-0015-8 CrossRefPubMed
4.
go back to reference Bouza C, López T, Magro A, Navalpotro L, Amate JM (2006) Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures: a systematic review. Eur Spine J 15(7):1050–1067. doi:10.1007/s00586-005-0048-x CrossRefPubMed Bouza C, López T, Magro A, Navalpotro L, Amate JM (2006) Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures: a systematic review. Eur Spine J 15(7):1050–1067. doi:10.​1007/​s00586-005-0048-x CrossRefPubMed
6.
go back to reference Chiras J, Depriester C, Weill A, Sola-Martinez MT, Deramond H (1997) Percutaneous vertebral surgery. Technics and indications. J Neuroradiol 24(1):45–59PubMed Chiras J, Depriester C, Weill A, Sola-Martinez MT, Deramond H (1997) Percutaneous vertebral surgery. Technics and indications. J Neuroradiol 24(1):45–59PubMed
7.
go back to reference Cooper C, Atkinson EJ, O’Fallon WM, Melton LJ 3d (1992) Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985–1989. J Bone Minor Res 7:221–227CrossRef Cooper C, Atkinson EJ, O’Fallon WM, Melton LJ 3d (1992) Incidence of clinically diagnosed vertebral fractures: a population-based study in Rochester, Minnesota, 1985–1989. J Bone Minor Res 7:221–227CrossRef
8.
go back to reference Cotten A, Dewatre F, Cortet B, Assaker R, Leblond D, Duquesnoy B, Chastanet P, Clarisse J (1996) Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and leakage of methyl methacrylate at clinical follow up. Radiology 200(2):525–530PubMed Cotten A, Dewatre F, Cortet B, Assaker R, Leblond D, Duquesnoy B, Chastanet P, Clarisse J (1996) Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and leakage of methyl methacrylate at clinical follow up. Radiology 200(2):525–530PubMed
9.
go back to reference Fourney, Schomer DF, Nader R, Chlan-Fourney J, Suki D, Ahrar K, Rhines LD, Goskaslan ZL (2003) Percutaneous vertebroplasty and kyphoplasty of painful vertebral body fractures patients. J Neurosurg 98(1 Suppl):21–30PubMed Fourney, Schomer DF, Nader R, Chlan-Fourney J, Suki D, Ahrar K, Rhines LD, Goskaslan ZL (2003) Percutaneous vertebroplasty and kyphoplasty of painful vertebral body fractures patients. J Neurosurg 98(1 Suppl):21–30PubMed
10.
go back to reference Galibert P, Deramond H, Rosat P, Le Gras D (1987) Note preminaire sur le traitement des angiomes vertebraux par vertebroplastie acrylique percutanee. Neurochirurgie 33(2):166–168PubMed Galibert P, Deramond H, Rosat P, Le Gras D (1987) Note preminaire sur le traitement des angiomes vertebraux par vertebroplastie acrylique percutanee. Neurochirurgie 33(2):166–168PubMed
11.
go back to reference Gangi A, Dietemann JL, Schultz A, Caffarati G, Roy C (1997) Value of percutaneous injection of acrylic cement using a pressure regulator. J Radiol 78(5):393–394PubMed Gangi A, Dietemann JL, Schultz A, Caffarati G, Roy C (1997) Value of percutaneous injection of acrylic cement using a pressure regulator. J Radiol 78(5):393–394PubMed
12.
go back to reference Gangi A, Guth S, Imbert JP, Marin H, Dietemann JL (2003) Percutaneous vertebroplasty: indications, technique, and results. Radiographics 23(e2):e10CrossRefPubMed Gangi A, Guth S, Imbert JP, Marin H, Dietemann JL (2003) Percutaneous vertebroplasty: indications, technique, and results. Radiographics 23(e2):e10CrossRefPubMed
13.
go back to reference Gangi A, Sabharwal T, Irani FG, Buy X, Morales JP, Adam A (2006) Standards of Practice Committee of the Society of Interventional Radiology Quality assurance guidelines for percutaneous vertebroplasty. Cardiovasc Intervent Radiol 29(2):173–178. doi:10.1007/s00270-005-0146-5 CrossRefPubMed Gangi A, Sabharwal T, Irani FG, Buy X, Morales JP, Adam A (2006) Standards of Practice Committee of the Society of Interventional Radiology Quality assurance guidelines for percutaneous vertebroplasty. Cardiovasc Intervent Radiol 29(2):173–178. doi:10.​1007/​s00270-005-0146-5 CrossRefPubMed
14.
go back to reference Grafin SR, Yuan HA, Reiley MA (2001) New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine (Phila Pa 1976) 26(14):1511–1515 Grafin SR, Yuan HA, Reiley MA (2001) New technologies in spine: kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures. Spine (Phila Pa 1976) 26(14):1511–1515
15.
go back to reference Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine (Phila Pa 1976) 31(17):1983–2001 Hulme PA, Krebs J, Ferguson SJ, Berlemann U (2006) Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine (Phila Pa 1976) 31(17):1983–2001
16.
go back to reference Jang JS, Lee SH, Jung SK (2002) Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: a case report of three cases. Spine (Phila Pa 1976) 27(19):416–418 Jang JS, Lee SH, Jung SK (2002) Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: a case report of three cases. Spine (Phila Pa 1976) 27(19):416–418
17.
go back to reference Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR (1999) Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group. Arch Intern Med 159(11):1215–1220CrossRefPubMed Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR (1999) Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group. Arch Intern Med 159(11):1215–1220CrossRefPubMed
18.
go back to reference Kasperk C, Nöldge G, Grafe I, Meeder P, Huber F, Nawroth P (2008) Indications and results of kypho- and vertebroplasty. Internist (Berl.) 49(10):1206, 1208–1210, 1212–1218. doi:10.1007/s00108-008-2116-x Kasperk C, Nöldge G, Grafe I, Meeder P, Huber F, Nawroth P (2008) Indications and results of kypho- and vertebroplasty. Internist (Berl.) 49(10):1206, 1208–1210, 1212–1218. doi:10.​1007/​s00108-008-2116-x
19.
21.
go back to reference Nevitt MC, Thompson DE, Black DM, Rubin SR, Ensrud K, Yates AJ, Cummings SR (2000) Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. Arch Intern Med 160(1):77–85CrossRefPubMed Nevitt MC, Thompson DE, Black DM, Rubin SR, Ensrud K, Yates AJ, Cummings SR (2000) Effect of alendronate on limited-activity days and bed-disability days caused by back pain in postmenopausal women with existing vertebral fractures. Fracture Intervention Trial Research Group. Arch Intern Med 160(1):77–85CrossRefPubMed
23.
24.
go back to reference Riggs BL, Melton LJ 3rd (1995) The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 17(5 Suppl):505S–511SCrossRefPubMed Riggs BL, Melton LJ 3rd (1995) The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 17(5 Suppl):505S–511SCrossRefPubMed
26.
go back to reference Röllinghoff M, Siewe J, Zarghooni K, Sobottke R, Alparslan Y, Eysel P, Delank KS (2009) Effectiveness, security and height restoration on fresh compression fractures-a comparative prospective study of vertebroplasty and kyphoplasty. Minim Invas Neurosurg 52(5-6):233–237. doi:10.1055/s-0029-1243631 CrossRef Röllinghoff M, Siewe J, Zarghooni K, Sobottke R, Alparslan Y, Eysel P, Delank KS (2009) Effectiveness, security and height restoration on fresh compression fractures-a comparative prospective study of vertebroplasty and kyphoplasty. Minim Invas Neurosurg 52(5-6):233–237. doi:10.​1055/​s-0029-1243631 CrossRef
28.
go back to reference Schnabel M, Weber M, Vassiliou T, Mann D, Kirschner M, Gotzen L, Kaluza G (2004) Diagnosis and therapy of acute complaints after “whiplash injury” in Germany. Results of a representative survey at surgical and trauma departments in Germany. Unfallchirurg 4:300–306. doi:10.1007/s00113-004-0740-z CrossRef Schnabel M, Weber M, Vassiliou T, Mann D, Kirschner M, Gotzen L, Kaluza G (2004) Diagnosis and therapy of acute complaints after “whiplash injury” in Germany. Results of a representative survey at surgical and trauma departments in Germany. Unfallchirurg 4:300–306. doi:10.​1007/​s00113-004-0740-z CrossRef
30.
go back to reference Silverman SL (1992) The clinical consequences of vertebral compression fracture. Bone 13(Suppl 2):27–31CrossRef Silverman SL (1992) The clinical consequences of vertebral compression fracture. Bone 13(Suppl 2):27–31CrossRef
31.
go back to reference Silverman SL, Piziak VK, Chen P et al (2005) Relationship of health related quality of life to prevalent and new or worsening back pain in postmenopausal women with osteoporosis. J Rheumatol 32:2405–2409PubMed Silverman SL, Piziak VK, Chen P et al (2005) Relationship of health related quality of life to prevalent and new or worsening back pain in postmenopausal women with osteoporosis. J Rheumatol 32:2405–2409PubMed
32.
go back to reference Stallmeyer MJ, Zoarski GH, Obuchowski AM (2003) Optimising patient selection in percutaneous vertebroplasty. J Vasc Intervent Radiol 14(6):683–696 Stallmeyer MJ, Zoarski GH, Obuchowski AM (2003) Optimising patient selection in percutaneous vertebroplasty. J Vasc Intervent Radiol 14(6):683–696
34.
go back to reference Yeom JS, Kim WJ, Choy WS, Lee CK, Chang BS, Kang JW (2003) Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fractures. J Bone Joint Surg (Br) 85(1):83–89. doi:10.1302/0301-620X.85B1.13026 CrossRef Yeom JS, Kim WJ, Choy WS, Lee CK, Chang BS, Kang JW (2003) Leakage of cement in percutaneous transpedicular vertebroplasty for painful osteoporotic compression fractures. J Bone Joint Surg (Br) 85(1):83–89. doi:10.​1302/​0301-620X.​85B1.​13026 CrossRef
Metadata
Title
Indications and contraindications for vertebroplasty and kyphoplasty
Authors
Marc Röllinghoff
Kourosh Zarghooni
Klaus Schlüter-Brust
Rolf Sobottke
Ulf Schlegel
Peer Eysel
Karl-Stefan Delank
Publication date
01-06-2010
Publisher
Springer-Verlag
Published in
Archives of Orthopaedic and Trauma Surgery / Issue 6/2010
Print ISSN: 0936-8051
Electronic ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-010-1083-6

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