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Open Access 01-09-2009 | Correspondence

Increased plasma amyloid-β₄₂ protein in sporadic inclusion body myositis

Authors: Wilson F. Abdo, Tom van Mierlo, Gerald J. Hengstman, H. Jurgen Schelhaas, Baziel G. van Engelen, Marcel M. Verbeek

Published in: Acta Neuropathologica | Issue 3/2009

Excerpt

Sporadic inclusion body myositis (s-IBM) is the most frequently acquired myopathy above the age of 50 years. Although the pathogenesis of s-IBM is largely unknown, an underlying myodegenerative process involving amyloid β protein (Aβ) accumulation has been proposed as a pathophysiological mechanism [1]. Here, we examined whether there are changes in the plasma levels of Aβ₄₂ and Aβ₄₀ in patients with s-IBM, patients with other inflammatory myopathies, and age-matched controls. …

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Title: Increased plasma amyloid-β42 protein in sporadic inclusion body myositis
Authors: Wilson F. Abdo
Tom van Mierlo
Gerald J. Hengstman
H. Jurgen Schelhaas
Baziel G. van Engelen
Marcel M. Verbeek
Publication date: 01-09-2009
Publisher: Springer-Verlag
Published in: Acta Neuropathologica / Issue 3/2009
Print ISSN: 0001-6322
Electronic ISSN: 1432-0533
DOI: https://doi.org/10.1007/s00401-009-0554-8

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Increased plasma amyloid-β₄₂ protein in sporadic inclusion body myositis

Excerpt

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

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