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Published in: European Journal of Nutrition 5/2019

01-08-2019 | Original Contribution

Еffects of fortified milk on cognitive abilities in school-aged children: results from a randomized-controlled trial

Authors: Dafina Petrova, María Asunción Bernabeu Litrán, Eduardo García-Mármol, Maria Rodríguez-Rodríguez, Belén Cueto-Martín, Eduardo López-Huertas, Andrés Catena, Juristo Fonollá

Published in: European Journal of Nutrition | Issue 5/2019

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Abstract

Background

Micronutrients such as vitamins and minerals and long-chain polyunsaturated omega-3 fatty acids (PUFAs) are essential for children’s brain development and cognitive functions. The current study investigated whether milk fortified with micronutrients and PUFA can result in improved cognitive function in mainstream school children.

Methods

One-hundred-and-nineteen children (age 8–14, 58 boys) were randomly allocated to a fortified milk group or a regular full milk control group. Participants consumed 0.6L/day of the milk for 5 months. We recorded relevant biochemical, anthropometric, and cognitive measures (working memory and processing speed) at the start of the study and at follow-up after 5 months.

Results

The fortified milk significantly increased docosahexaenoic acid (DHA) (change from baseline of 28% [95% CI 17–39%] vs. −6% [95% CI − 13 to 0%] in the control group) and serum 25OH-vitamin D concentrations (41% [95% CI 30–52%] vs. 21% [95% CI 11–30%] in the control group). The fortified milk improved working memory on one of two tests (32% [95% CI 17–47%] vs. 13% [95% CI 6–19%] in the control group). The fortified milk also indirectly increased processing speed on one of two tests; this effect was small and completely mediated by increases in 25OH-vitamin D concentrations.

Conclusions

These results suggest that fortifying milk with micronutrients and PUFA could be an effective and practical way to aid children’s cognitive development.
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Metadata
Title
Еffects of fortified milk on cognitive abilities in school-aged children: results from a randomized-controlled trial
Authors
Dafina Petrova
María Asunción Bernabeu Litrán
Eduardo García-Mármol
Maria Rodríguez-Rodríguez
Belén Cueto-Martín
Eduardo López-Huertas
Andrés Catena
Juristo Fonollá
Publication date
01-08-2019
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nutrition / Issue 5/2019
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-018-1734-x

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