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European Journal of Nutrition
Published in: European Journal of Nutrition 2/2017

Open Access 01-03-2017 | Review

Fruitflow®: the first European Food Safety Authority-approved natural cardio-protective functional ingredient

Authors: Niamh O’Kennedy, Daniel Raederstorff, Asim K. Duttaroy

Published in: European Journal of Nutrition | Issue 2/2017

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Abstract

Hyperactive platelets, in addition to their roles in thrombosis, are also important mediators of atherogenesis. Antiplatelet drugs are not suitable for use where risk of a cardiovascular event is relatively low. It is therefore important to find alternative safe antiplatelet inhibitors for the vulnerable population who has hyperactive platelets in order to reduce the risk of cardiovascular disease. Potent antiplatelet factors were identified in water-soluble tomato extract (Fruitflow®), which significantly inhibited platelet aggregation. Human volunteer studies demonstrated the potency and bioavailability of active compounds in Fruitflow®. Fruitflow® became the first product in Europe to obtain an approved, proprietary health claim under Article 13(5) of the European Health Claims Regulation 1924/2006 on nutrition and health claims made on foods. Fruitflow® is now commercially available in different countries worldwide. In addition to its reduction in platelet reactivity, Fruitflow® contains anti-angiotensin-converting enzyme and anti-inflammatory factors, making it an effective and natural cardio-protective functional food.
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Metadata
Title
Fruitflow®: the first European Food Safety Authority-approved natural cardio-protective functional ingredient
Authors
Niamh O’Kennedy
Daniel Raederstorff
Asim K. Duttaroy
Publication date
01-03-2017
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Nutrition / Issue 2/2017
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-016-1265-2

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