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01-04-2021 | Letter to the Editors

Right insular cortex atrophy in Takotsubo syndrome: a possible pathogenesis of increased sympathetic nervous system activity?

Authors: Michiaki Nagai, Carola Y. Förster, Keigo Dote

Published in: Clinical Research in Cardiology | Issue 4/2021

Excerpt

We read an interesting manuscript by Dichtl [1], who reported volumetric and functional changes of the right insular cortex (Ic) based on anatomical and resting-state functional magnetic resonance (fMRI) imaging in Takotsubo syndrome (TTS). Although the relationships of the right anterior Ic atrophy and the left amygdala atrophy with sympatho-vagal autonomic instability were suggested to underlie in TTS, several points should be taken into account to understand the pathophysiology of TTS in relation to central autonomic network (CAN) presented by Dichtl [1]. …

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Nagai M, Dote K, Kato M, Sasaki S, Oda N, Kagawa E, Nakano Y, Yamane A, Higashihara T, Miyauchi S, Tsuchiya A, Harada W, Kario K (2017) The insular cortex and Takotsubo cardiomyopathy. Curr Pharm Des 23:879–888CrossRef

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Title: Right insular cortex atrophy in Takotsubo syndrome: a possible pathogenesis of increased sympathetic nervous system activity?
Authors: Michiaki Nagai
Carola Y. Förster
Keigo Dote
Publication date: 01-04-2021
Publisher: Springer Berlin Heidelberg
Published in: Clinical Research in Cardiology / Issue 4/2021
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-020-01665-2

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