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Published in:

01-01-2015 | Review

Clinical significance of conduction disturbances after aortic valve intervention: current evidence

Authors: Manuel Martinez-Selles, Peter Bramlage, Martin Thoenes, Gerhard Schymik

Published in: Clinical Research in Cardiology | Issue 1/2015

Abstract

The occurrence of new conduction abnormalities that lead to the requirement for new permanent pacemaker implantation (PPI) has been reported to be the most frequent complication following transcatheter aortic valve implantation (TAVI). However, the reasons and clinical significance of TAVI-induced conduction disturbances and PPI are yet to be fully delineated. This review aims to evaluate the procedure- and patient-related factors that may contribute to the development of aberrant atrioventricular conduction following TAVI as well as its clinical consequences.

Nkomo VT, Gardin JM, Skelton TN, Gottdiener JS, Scott CG, Enriquez-Sarano M (2006) Burden of valvular heart diseases: a population-based study. Lancet 368:1005–1011PubMedCrossRef

Osnabrugge RL, Mylotte D, Head SJ, Van Mieghem NM, Nkomo VT, LeReun CM, Bogers AJ, Piazza N et al (2013) Aortic stenosis in the elderly: disease prevalence and number of candidates for transcatheter aortic valve replacement: a meta-analysis and modeling study. J Am Coll Cardiol 62:1002–1012PubMedCrossRef

Cribier A (2012) Development of transcatheter aortic valve implantation (TAVI): a 20-year odyssey. Arch Cardiovasc Dis 105:146–152PubMedCrossRef

McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, Falk V, Filippatos G et al (2012) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J 33:1787–1847PubMedCrossRef

Tang GH, Lansman SL, Cohen M, Spielvogel D, Cuomo L, Ahmad H, Dutta T (2013) Transcatheter aortic valve replacement: current developments, ongoing issues, future outlook. Cardiol Rev 21:55–76PubMedCrossRef

Neragi-Miandoab S, Michler RE (2013) A review of most relevant complications of transcatheter aortic valve implantation. ISRN Cardiol 2013:956252PubMedCentralPubMed

Kappetein AP, Head SJ, Genereux P, Piazza N, van Mieghem NM, Blackstone EH, Brott TG, Cohen DJ et al (2013) Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document. J Thorac Cardiovasc Surg 145:6–23PubMedCrossRef

Roten L, Meier B (2014) Left bundle branch block after transcatheter aortic valve implantation: still a matter of concern? JACC Cardiovasc Interv 7:137–139PubMedCrossRef

Colombo A, Latib A (2012) Left bundle branch block after transcatheter aortic valve implantation: inconsequential or a clinically important endpoint? J Am Coll Cardiol 60:1753–1755PubMedCrossRef

10.

Fraccaro C, Napodano M, Tarantini G (2013) Conduction disorders in the setting of transcatheter aortic valve implantation: a clinical perspective. Catheter Cardiovasc Interv 81:1217–1223PubMedCrossRef

11.

Khatri PJ, Webb JG, Rodes-Cabau J, Fremes SE, Ruel M, Lau K, Guo H, Wijeysundera HC et al (2013) Adverse effects associated with transcatheter aortic valve implantation: a meta-analysis of contemporary studies. Ann Intern Med 158:35–46PubMedCrossRef

12.

Van Mieghem NM, Head SJ, de Jong W, van Domburg RT, Serruys PW, de Jaegere PP, Jordaens L, Takkenberg JJ et al (2012) Persistent annual permanent pacemaker implantation rate after surgical aortic valve replacement in patients with severe aortic stenosis. Ann Thorac Surg 94:1143–1149PubMedCrossRef

13.

Roten L, Stortecky S, Scarcia F, Kadner A, Tanner H, Delacretaz E, Meier B, Windecker S et al (2012) Atrioventricular conduction after transcatheter aortic valve implantation and surgical aortic valve replacement. J Cardiovasc Electrophysiol 23:1115–1122PubMedCrossRef

14.

Bagur R, Rodes-Cabau J, Gurvitch R, Dumont E, Velianou JL, Manazzoni J, Toggweiler S, Cheung A et al (2012) Need for permanent pacemaker as a complication of transcatheter aortic valve implantation and surgical aortic valve replacement in elderly patients with severe aortic stenosis and similar baseline electrocardiographic findings. JACC Cardiovasc Interv 5:540–551PubMedCrossRef

15.

Simms AD, Hogarth AJ, Hudson EA, Worsnop VL, Blackman DJ, O’Regan DJ, Tayebjee MH (2013) Ongoing requirement for pacing post-transcatheter aortic valve implantation and surgical aortic valve replacement. Interact Cardiovasc Thorac Surg 17:328–333PubMedCentralPubMedCrossRef

16.

El-Khally Z, Thibault B, Staniloae C, Theroux P, Dubuc M, Roy D, Guerra P, Macle L et al (2004) Prognostic significance of newly acquired bundle branch block after aortic valve replacement. Am J Cardiol 94:1008–1011PubMedCrossRef

17.

Kalavrouziotis D, Li D, Buth KJ, Legare JF (2009) The European System for Cardiac Operative Risk Evaluation (EuroSCORE) is not appropriate for withholding surgery in high-risk patients with aortic stenosis: a retrospective cohort study. J Cardiothorac Surg 4:32PubMedCentralPubMedCrossRef

18.

Akin I, Kische S, Paranskaya L, Schneider H, Rehders TC, Trautwein U, Turan G, Bansch D et al (2012) Predictive factors for pacemaker requirement after transcatheter aortic valve implantation. BMC Cardiovasc Disord 12:87PubMedCentralPubMedCrossRef

19.

Baan J Jr, Yong ZY, Koch KT, Henriques JP, Bouma BJ, Vis MM, Cocchieri R, Piek JJ et al (2010) Factors associated with cardiac conduction disorders and permanent pacemaker implantation after percutaneous aortic valve implantation with the CoreValve prosthesis. Am Heart J 159:497–503PubMedCrossRef

20.

Bleiziffer S, Ruge H, Horer J, Hutter A, Geisbusch S, Brockmann G, Mazzitelli D, Bauernschmitt R et al (2010) Predictors for new-onset complete heart block after transcatheter aortic valve implantation. JACC Cardiovasc Interv 3:524–530PubMedCrossRef

21.

Buellesfeld L, Stortecky S, Heg D, Hausen S, Mueller R, Wenaweser P, Pilgrim T, Gloekler S et al (2012) Impact of permanent pacemaker implantation on clinical outcome among patients undergoing transcatheter aortic valve implantation. J Am Coll Cardiol 60:493–501PubMedCrossRef

22.

Franzoni I, Latib A, Maisano F, Costopoulos C, Testa L, Figini F, Giannini F, Basavarajaiah S et al (2013) Comparison of incidence and predictors of left bundle branch block after transcatheter aortic valve implantation using the CoreValve versus the Edwards valve. Am J Cardiol 112:554–559PubMedCrossRef

23.

Goldenberg G, Kusniec J, Kadmon E, Golovchiner G, Zabarsky R, Nevzorov R, Vaknin H, Assali A et al (2013) Pacemaker implantation after transcatheter aortic valve implantation. Am J Cardiol 112:1632–1634PubMedCrossRef

24.

Grube E, Naber C, Abizaid A, Sousa E, Mendiz O, Lemos P, Kalil Filho R, Mangione J et al (2011) Feasibility of transcatheter aortic valve implantation without balloon pre-dilation: a pilot study. JACC Cardiovasc Interv 4:751–757PubMedCrossRef

25.

Koos R, Mahnken AH, Aktug O, Dohmen G, Autschbach R, Marx N, Hoffmann R (2011) Electrocardiographic and imaging predictors for permanent pacemaker requirement after transcatheter aortic valve implantation. J Heart Valve Dis 20:83–90PubMed

26.

Liang M, Devlin G, Pasupati S (2012) The incidence of transcatheter aortic valve implantation-related heart block in self-expandable Medtronic CoreValve and balloon-expandable Edwards valves. J Invasive Cardiol 24:173–176PubMed

27.

Mouillet G, Lellouche N, Lim P, Meguro K, Yamamoto M, Deux JF, Monin JL, Bergoend E et al (2013) Patients without prolonged QRS after TAVI with CoreValve device do not experience high-degree atrio-ventricular block. Catheter Cardiovasc Interv 81:882–887PubMedCrossRef

28.

Pereira E, Ferreira N, Caeiro D, Primo J, Adao L, Oliveira M, Goncalves H, Ribeiro J et al (2013) Transcatheter aortic valve implantation and requirements of pacing over time. Pacing Clin Electrophysiol 36:559–569PubMedCrossRef

29.

Piazza N, Onuma Y, Jesserun E, Kint PP, Maugenest AM, Anderson RH, de Jaegere PP, Serruys PW (2008) Early and persistent intraventricular conduction abnormalities and requirements for pacemaking after percutaneous replacement of the aortic valve. JACC Cardiovasc Interv 1:310–316PubMedCrossRef

30.

Piazza N, Nuis RJ, Tzikas A, Otten A, Onuma Y, Garcia-Garcia H, Schultz C, van Domburg R et al (2010) Persistent conduction abnormalities and requirements for pacemaking 6 months after transcatheter aortic valve implantation. Eurointervention 6:475–484PubMedCrossRef

31.

Roten L, Wenaweser P, Delacretaz E, Hellige G, Stortecky S, Tanner H, Pilgrim T, Kadner A et al (2010) Incidence and predictors of atrioventricular conduction impairment after transcatheter aortic valve implantation. Am J Cardiol 106:1473–1480PubMedCrossRef

32.

Saia F, Lemos PA, Bordoni B, Cervi E, Boriani G, Ciuca C, Taglieri N, Mariani J Jr et al (2012) Transcatheter aortic valve implantation with a self-expanding nitinol bioprosthesis: prediction of the need for permanent pacemaker using simple baseline and procedural characteristics. Catheter Cardiovasc Interv 79:712–719PubMedCrossRef

33.

Schroeter T, Linke A, Haensig M, Merk DR, Borger MA, Mohr FW, Schuler G (2012) Predictors of permanent pacemaker implantation after Medtronic CoreValve bioprosthesis implantation. Europace 14:1759–1763PubMedCrossRef

34.

Houthuizen P, Van Garsse LA, Poels TT, de Jaegere P, van der Boon RM, Swinkels BM, Ten Berg JM, van der Kley F et al (2012) Left bundle-branch block induced by transcatheter aortic valve implantation increases risk of death. Circulation 126:720–728PubMedCrossRef

35.

van der Boon RM, Van Mieghem NM, Theuns DA, Nuis RJ, Nauta ST, Serruys PW, Jordaens L, van Domburg RT et al (2013) Pacemaker dependency after transcatheter aortic valve implantation with the self-expanding Medtronic CoreValve System. Int J Cardiol 168:1269–1273PubMedCrossRef

36.

Ferreira ND, Caeiro D, Adao L, Oliveira M, Goncalves H, Ribeiro J, Teixeira M, Albuquerque A et al (2010) Incidence and predictors of permanent pacemaker requirement after transcatheter aortic valve implantation with a self-expanding bioprosthesis. Pacing Clin Electrophysiol 33:1364–1372PubMedCrossRef

37.

Erkapic D, Kim WK, Weber M, Mollmann H, Berkowitsch A, Zaltsberg S, Pajitnev DJ, Rixe J et al (2010) Electrocardiographic and further predictors for permanent pacemaker requirement after transcatheter aortic valve implantation. Europace 12:1188–1190PubMedCrossRef

38.

Nijhoff F, Agostoni P, Amrane H, Latib A, Testa L, Oreglia JA, De Marco F, Samim M et al (2013) Transcatheter aortic valve implantation in patients with severe aortic valve stenosis and large aortic annulus, using the self-expanding 31-mm Medtronic CoreValve prosthesis: first clinical experience. J Thorac Cardiovasc Surg. doi:10.1016/j.jtcvs.2013.09.059

39.

Blackman DJ, Baxter PD, Gale CP, Moat NE, Maccarthy PA, Hildick-Smith D, Trivedi U, Cunningham D et al (2014) Do outcomes from transcatheter aortic valve implantation vary according to access route and valve type? The UK TAVI Registry. J Interv Cardiol 27:86–95PubMedCrossRef

40.

Kraus JDF, Hammerer M, Schneider J, Hoppe U, Strohmer B (2013) Pacemaker dependency after transaortic valve implantation. Osterreichische Kardiologische Gesellschaft Jahrestagung Wiener Med Wochenschr 125:s43–s43

41.

Bjerre Thygesen J, Loh PH, Cholteesupachai J, Franzen O, Sondergaard L (2014) Reevaluation of the indications for permanent pacemaker implantation after transcatheter aortic valve implantation. J Invasive Cardiol 26:94–99PubMed

42.

Gutierrez M, Rodes-Cabau J, Bagur R, Doyle D, DeLarochelliere R, Bergeron S, Lemieux J, Villeneuve J et al (2009) Electrocardiographic changes and clinical outcomes after transapical aortic valve implantation. Am Heart J 158:302–308PubMedCrossRef

43.

Laynez A, Ben-Dor I, Barbash IM, Hauville C, Sardi G, Maluenda G, Xue Z, Satler LF et al (2012) Frequency of conduction disturbances after Edwards SAPIEN percutaneous valve implantation. Am J Cardiol 110:1164–1168PubMedCrossRef

44.

Binder RK, Webb JG, Toggweiler S, Freeman M, Barbanti M, Willson AB, Alhassan D, Hague CJ et al (2013) Impact of post-implant SAPIEN XT geometry and position on conduction disturbances, hemodynamic performance, and paravalvular regurgitation. JACC Cardiovasc Interv 6:462–468PubMedCrossRef

45.

Urena M, Webb JG, Tamburino C, Munoz-Garcia AJ, Cheema A, Dager AE, Serra V, Amat-Santos IJ et al (2014) Permanent pacemaker implantation after transcatheter aortic valve implantation: impact on late clinical outcomes and left ventricular function. Circulation 129:1233–1243PubMedCrossRef

46.

Martinez-Selles M, Gomez Doblas JJ, Carro Hevia A, Garcia de la Villa B, Ferreira-Gonzalez I, Alonso Tello A, Andion Ogando R, Ripoll Vera T et al (2014) Prospective registry of symptomatic severe aortic stenosis in octogenarians: a need for intervention. J Intern Med 275:608–620PubMedCrossRef

47.

Jilaihawi H, Chakravarty T, Weiss RE, Fontana GP, Forrester J, Makkar RR (2012) Meta-analysis of complications in aortic valve replacement: comparison of Medtronic-Corevalve, Edwards-Sapien and surgical aortic valve replacement in 8,536 patients. Catheter Cardiovasc Interv 80:128–138PubMedCrossRef

48.

Fournial JF, Brodaty D, Chomette G, Tereau Y, Cabrol C, Acar J (1979) Conduction disorders after aortic valve replacement. Apropos of 200 cases. Arch Mal Coeur Vaiss 72:4–11PubMed

49.

Thomas JL, Dickstein RA, Parker FB Jr, Potts JL, Poirier RA, Fruehan CT, Eich RH (1982) Prognostic significance of the development of left bundle conduction defects following aortic valve replacement. J Thorac Cardiovasc Surg 84:382–386PubMed

50.

Kolh P, Kerzmann A, Honore C, Comte L, Limet R (2007) Aortic valve surgery in octogenarians: predictive factors for operative and long-term results. Eur J Cardiothorac Surg 31:600–606PubMedCrossRef

51.

Aktug O, Dohmen G, Brehmer K, Koos R, Altiok E, Deserno V, Herpertz R, Autschbach R et al (2012) Incidence and predictors of left bundle branch block after transcatheter aortic valve implantation. Int J Cardiol 160:26–30PubMedCrossRef

52.

Nuis RJ, Van Mieghem NM, Schultz CJ, Tzikas A, Van der Boon RM, Maugenest AM, Cheng J, Piazza N et al (2011) Timing and potential mechanisms of new conduction abnormalities during the implantation of the Medtronic CoreValve System in patients with aortic stenosis. Eur Heart J 32:2067–2074PubMedCrossRef

53.

Tzikas A, van Dalen BM, Van Mieghem NM, Gutierrez-Chico JL, Nuis RJ, Kauer F, Schultz C, Serruys PW et al (2011) Frequency of conduction abnormalities after transcatheter aortic valve implantation with the Medtronic-CoreValve and the effect on left ventricular ejection fraction. Am J Cardiol 107:285–289PubMedCrossRef

54.

Urena M, Mok M, Serra V, Dumont E, Nombela-Franco L, DeLarochelliere R, Doyle D, Igual A et al (2012) Predictive factors and long-term clinical consequences of persistent left bundle branch block following transcatheter aortic valve implantation with a balloon-expandable valve. J Am Coll Cardiol 60:1743–1752PubMedCrossRef

55.

Nazif TM, Williams MR, Hahn RT, Kapadia S, Babaliaros V, Rodes-Cabau J, Szeto WY, Jilaihawi H et al (2014) Clinical implications of new-onset left bundle branch block after transcatheter aortic valve replacement: analysis of the PARTNER experience. Eur Heart J 32:1599–1607CrossRef

56.

Mukherjee C, Busse H, Mende M, Banusch J, Feussner M, Ender J (2013) Incidence and outcome of artioventricular block after transcatheter aortic valve implantation (TAVI): analysis in 994 patients. In: EACTA, pp 139–140

57.

Schwerg M, Baldenhofer G, Dreger H, Bondke H, Stangl K, Laule M, Melzer C (2013) Complete atrioventricular block after TAVI: when is pacemaker implantation safe? Pacing Clin Electrophysiol 36:898–903PubMedCrossRef

58.

Bagur R, Manazzoni JM, Dumont E, Doyle D, Perron J, Dagenais F, Mathieu P, Baillot R et al (2011) Permanent pacemaker implantation following isolated aortic valve replacement in a large cohort of elderly patients with severe aortic stenosis. Heart 97:1687–1694PubMedCrossRef

59.

Onorati F, D’Errigo P, Barbanti M, Rosato S, Covello DR, Maraschini A, Ranucci M, Grossi C et al (2013) Results differ between transaortic and open surgical aortic valve replacement in women. Ann Thorac Surg 96:1336–1342PubMedCrossRef

60.

Brignole M, Auricchio A, Baron-Esquivias G, Bordachar P, Boriani G, Breithardt OA, Cleland J, Deharo JC et al (2013) 2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy: the task force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA). Europace 15:1070–1118PubMedCrossRef

61.

Ghadimi K, Patel PA, Gutsche JT, Sophocles A, Anwaruddin S, Szeto WY, Augoustides JG (2013) Perioperative conduction disturbances after transcatheter aortic valve replacement. J Cardiothorac Vasc Anesth 27:1414–1420PubMedCrossRef

62.

Anderson RH, Boyett MR, Dobrzynski H, Moorman AF (2013) The anatomy of the conduction system: implications for the clinical cardiologist. J Cardiovasc Transl Res 6:187–196PubMedCrossRef

63.

Moreno R, Dobarro D, Lopez de Sa E, Prieto M, Morales C, Calvo Orbe L, Moreno-Gomez I, Filgueiras D et al (2009) Cause of complete atrioventricular block after percutaneous aortic valve implantation: insights from a necropsy study. Circulation 120:e29–e30PubMedCrossRef

64.

Toutouzas K, Synetos A, Tousoulis D, Latsios G, Brili S, Mastrokostopoulos A, Karanasos A, Sideris S et al (2014) Predictors for permanent pacemaker implantation after core valve implantation in patients without preexisting ECG conduction disturbances: the role of a new echocardiographic index. Int J Cardiol 172:601–603PubMedCrossRef

65.

Tzamtzis S, Viquerat J, Yap J, Mullen MJ, Burriesci G (2013) Numerical analysis of the radial force produced by the Medtronic-CoreValve and Edwards-SAPIEN after transcatheter aortic valve implantation (TAVI). Med Eng Phys 35:125–130PubMedCrossRef

66.

Buellesfeld L, Stortecky S, Kalesan B, Gloekler S, Khattab AA, Nietlispach F, Delfine V, Huber C et al (2013) Aortic root dimensions among patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. JACC Cardiovasc Interv 6:72–83PubMedCrossRef

67.

Breithardt G, Breithardt OA (2012) Left bundle branch block, an old-new entity. J Cardiovasc Transl Res 5:107–116PubMedCentralPubMedCrossRef

68.

Erkapic D, De Rosa S, Kelava A, Lehmann R, Fichtlscherer S, Hohnloser SH (2012) Risk for permanent pacemaker after transcatheter aortic valve implantation: a comprehensive analysis of the literature. J Cardiovasc Electrophysiol 23:391–397PubMedCrossRef

69.

Moat NE, Ludman P, de Belder MA, Bridgewater B, Cunningham AD, Young CP, Thomas M, Kovac J et al (2011) Long-term outcomes after transcatheter aortic valve implantation in high-risk patients with severe aortic stenosis: the U.K. TAVI (United Kingdom Transcatheter Aortic Valve Implantation) Registry. J Am Coll Cardiol 58:2130–2138PubMedCrossRef

70.

Elmariah S, Palacios IF, McAndrew T, Hueter I, Inglessis I, Baker JN, Kodali S, Leon MB et al (2013) Outcomes of transcatheter and surgical aortic valve replacement in high-risk patients with aortic stenosis and left ventricular dysfunction: results from the Placement of Aortic Transcatheter Valves (PARTNER) trial (cohort A). Circ Cardiovasc Interv 6:604–614PubMedCrossRef

71.

Hoffmann R, Herpertz R, Lotfipour S, Aktug O, Brehmer K, Lehmacher W, Autschbach R, Marx N et al (2012) Impact of a new conduction defect after transcatheter aortic valve implantation on left ventricular function. JACC Cardiovasc Interv 5:1257–1263PubMedCrossRef

72.

Khawaja MZ, Rajani R, Cook A, Khavandi A, Moynagh A, Chowdhary S, Spence MS, Brown S et al (2011) Permanent pacemaker insertion after CoreValve transcatheter aortic valve implantation: incidence and contributing factors (the UK CoreValve Collaborative). Circulation 123:951–960PubMedCrossRef

73.

Sinning JM, Werner N, Nickenig G, Grube E (2012) Next-generation transcatheter heart valves: current trials in Europe and the USA. Methodist Debakey Cardiovasc J 8:9–12PubMedCentralPubMedCrossRef

74.

Binder RK, Rodes-Cabau J, Wood DA, Mok M, Leipsic J, De Larochelliere R, Toggweiler S, Dumont E et al (2013) Transcatheter aortic valve replacement with the SAPIEN 3: a new balloon-expandable transcatheter heart valve. JACC Cardiovasc Interv 6:293–300PubMedCrossRef

75.

Falk V, Walther T, Schwammenthal E, Strauch J, Aicher D, Wahlers T, Schafers J, Linke A et al (2011) Transapical aortic valve implantation with a self-expanding anatomically oriented valve. Eur Heart J 32:878–887PubMedCrossRef

76.

Willson AB, Rodes-Cabau J, Wood DA, Leipsic J, Cheung A, Toggweiler S, Binder RK, Freeman M et al (2012) Transcatheter aortic valve replacement with the St. Jude Medical Portico valve: first-in-human experience. J Am Coll Cardiol 60:581–586PubMedCrossRef

77.

Treede H, Mohr FW, Baldus S, Rastan A, Ensminger S, Arnold M, Kempfert J, Figulla HR (2012) Transapical transcatheter aortic valve implantation using the JenaValve system: acute and 30-day results of the multicentre CE-mark study. Eur J Cardiothorac Surg 41:e131–e138PubMedCrossRef

78.

Schofer J, Schluter M, Treede H, Franzen OW, Tubler T, Pascotto A, Low RI, Bolling SF et al (2008) Retrograde transarterial implantation of a nonmetallic aortic valve prosthesis in high-surgical-risk patients with severe aortic stenosis: a first-in-man feasibility and safety study. Circ Cardiovasc Interv 1:126–133PubMedCrossRef

79.

Zembala MO, Piegza J, Waclawski J, Hawranek M, Hilker M, Niklewski T, Glowacki J, Parys M et al (2014) Symetis Acurate Transapical Aortic Valve: the initial experience with a second generation of transcatheter aortic valve replacement device. Kardiol Pol 72:187–193PubMedCrossRef

80.

Seiffert M, Conradi L, Kloth B, Koschyk D, Schirmer J, Schnabel RB, Blankenberg S, Reichenspurner H et al (2014) Single-centre experience with next-generation devices for transapical aortic valve implantation. Eur J Cardiothorac Surg [Epub ahead of print]

81.

Orlando R, Pennant M, Rooney S, Khogali S, Bayliss S, Hassan A, Moore D, Barton P (2013) Cost-effectiveness of transcatheter aortic valve implantation (TAVI) for aortic stenosis in patients who are high risk or contraindicated for surgery: a model-based economic evaluation. Health Technol Assess 17:1–86PubMedCrossRef

82.

Osman F, Krishnamoorthy S, Nadir A, Mullin P, Morley-Davies A, Creamer J (2010) Safety and cost-effectiveness of same day permanent pacemaker implantation. Am J Cardiol 106:383–385PubMedCrossRef

83.

Greenspon AJ, Patel JD, Lau E, Ochoa JA, Frisch DR, Ho RT, Pavri BB, Kurtz SM (2012) Trends in permanent pacemaker implantation in the United States from 1993 to 2009: increasing complexity of patients and procedures. J Am Coll Cardiol 60:1540–1545PubMedCrossRef

84.

Naber CTM, Bramlage P, Wasem J (2014) The impact of TAVI related permanent pacemaker implantation on the German healthcare system. Eurointervention 14A-OP319

Title: Clinical significance of conduction disturbances after aortic valve intervention: current evidence
Authors: Manuel Martinez-Selles
Peter Bramlage
Martin Thoenes
Gerhard Schymik
Publication date: 01-01-2015
Publisher: Springer Berlin Heidelberg
Published in: Clinical Research in Cardiology / Issue 1/2015
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-014-0739-6

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