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01-11-2014 | Original Paper

Ruptures of the device landing zone in patients undergoing transcatheter aortic valve implantation: an analysis of TAVI Karlsruhe (TAVIK) patients

Authors: Gerhard Schymik, Martin Heimeshoff, Peter Bramlage, Rainer Wondraschek, Tim Süselbeck, Jan Gerhardus, Armin Luik, Herbert Posival, Claus Schmitt, Holger Schröfel

Published in: Clinical Research in Cardiology | Issue 11/2014

Abstract

Background

Aortic rupture of the device landing zone is a rare complication of transcatheter aortic valve implantation (TAVI) and it is associated with significant mortality.

Methods

This study reports on the experience of a single-center in a case series of more than 1,000 implants. We explored patient and procedural characteristics aiming at identifying variables that increase the risk for aortic root rupture.

Results

Among a total of 1,000 TAVI procedures, six patients (0.6 %) had a rupture of the device landing zone. Five of these patients received the balloon-expandable Edwards SAPIEN valve (5/813; 0.62 %) of which four had a supraannular and one a subannular rupture. One patient received the self-expanding Medtronic CoreValve (1/199; 0.5 %; p = n.s. vs. SAPIEN) and had an annular rupture. Factors that were associated with aortic rupture were: (1) the relative size of the valve compared with the aortic annulus and its geometric form; (2) the need for post-dilation of the new valve because of paravalvular leakage; and (3) the location and severity of calcification. We determined, to avoid aortic rupture, caution may be necessary in the presence of the following conditions: (1) flat sinuses of Valsalva and severe calcifications of either the body or the free edge of the aortic cusps (supraannular rupture); (2) an ellipsoid annulus and bulky calcifications on either the base of the cusps or the rim of the annulus (annular rupture); and (3) a narrow left-ventricular outflow tract (LVOT) and bulky calcification of the LVOT (subannular rupture). After considering these precautions, we observed no case of aortic root rupture in the following 600 cases.

Conclusion

The data indicate that to reduce the frequency of aortic rupture, a careful pre-procedural planning appears essential to avoid this serious and potentially deleterious complication.

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Title: Ruptures of the device landing zone in patients undergoing transcatheter aortic valve implantation: an analysis of TAVI Karlsruhe (TAVIK) patients
Authors: Gerhard Schymik
Martin Heimeshoff
Peter Bramlage
Rainer Wondraschek
Tim Süselbeck
Jan Gerhardus
Armin Luik
Herbert Posival
Claus Schmitt
Holger Schröfel
Publication date: 01-11-2014
Publisher: Springer Berlin Heidelberg
Published in: Clinical Research in Cardiology / Issue 11/2014
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-014-0729-8

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Methods

Results

Conclusion

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