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Published in: Clinical Research in Cardiology 6/2009

01-06-2009 | Original Paper

EuroSCORE overestimates the risk of cardiac surgery: results from the national registry of the German Society of Thoracic and Cardiovascular Surgery

Authors: J. F. Gummert, A. Funkat, B. Osswald, A. Beckmann, W. Schiller, A. Krian, F. Beyersdorf, A. Haverich, J. Cremer

Published in: Clinical Research in Cardiology | Issue 6/2009

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Abstract

Objective

The EuroSCORE risk stratification model has been developed in 1995 and is still widely used to assess individual patient risk prior to cardiac surgery. Furthermore, the score advanced to a decision tool to determine so-called “high-risk patients” and in consequence serves as an important selection criterion in new technologies, such as the catheter-based aortic valve replacement. Several studies with relatively small patient numbers showed a substantial overestimation of risk by the EuroSCORE. The aim of our study was to evaluate whether the nationwide data support this finding.

Methods

A subgroup of the registry of the German Society of Thoracic and Cardiovascular Surgery from 2006 and 2007, with 32,806 patients undergoing isolated coronary surgery and isolated aortic valve replacement was investigated.

Results

The overall hospital mortality in isolated coronary surgery in this patient cohort (n = 26,501 patients) was 2.6% (n = 695). The overall hospital mortality in isolated aortic valve replacement in this patient cohort (n = 6,305 patients) was 3.9% (n = 245). The logistic EuroSCORE predicted a proportion of 5.2% for patients with isolated CABG and 7.3% for patients with isolated aortic valve replacement. The area under the receiver operating characteristic curve was 0.77 for isolated CABG procedures and 0.69 for isolated valve procedures, supporting the substantial lack of predictive value of the EuroSCORE.

Conclusion

The logistic EuroSCORE insufficiently evaluates the risk of the current patient population and therefore should be carefully used as a tool for important therapeutic decision-making.
Literature
1.
go back to reference Alexiou K, Kappert U, Staroske A, Joskowiak D, Wilbring M, Matschke K et al (2008) Coronary surgery for acute coronary syndrome: which determinants of outcome remain? Clin Res Cardiol 97(9):601–608PubMedCrossRef Alexiou K, Kappert U, Staroske A, Joskowiak D, Wilbring M, Matschke K et al (2008) Coronary surgery for acute coronary syndrome: which determinants of outcome remain? Clin Res Cardiol 97(9):601–608PubMedCrossRef
2.
go back to reference Bhatti F, Grayson AD, Grotte G, Fabri BM, Au J, Jones M et al (2006) The logistic EuroSCORE in cardiac surgery: how well does it predict operative risk? Heart 92(12):1817–1820PubMedCrossRef Bhatti F, Grayson AD, Grotte G, Fabri BM, Au J, Jones M et al (2006) The logistic EuroSCORE in cardiac surgery: how well does it predict operative risk? Heart 92(12):1817–1820PubMedCrossRef
3.
4.
go back to reference Bruch C, Bruch C, Sindermann J, Breithardt G, Gradaus R (2007) Prevalence and prognostic impact of comorbidities in heart failure patients with implantable cardioverter defibrillator. Europace 9(8):681–686PubMedCrossRef Bruch C, Bruch C, Sindermann J, Breithardt G, Gradaus R (2007) Prevalence and prognostic impact of comorbidities in heart failure patients with implantable cardioverter defibrillator. Europace 9(8):681–686PubMedCrossRef
5.
go back to reference Collart F, Feier H, Kerbaul F, Mouly-Bandini A, Riberi A, Mesana TG et al (2005) Valvular surgery in octogenarians: operative risks factors, evaluation of Euroscore and long term results. Eur J Cardiothorac Surg 27(2):276–280PubMedCrossRef Collart F, Feier H, Kerbaul F, Mouly-Bandini A, Riberi A, Mesana TG et al (2005) Valvular surgery in octogenarians: operative risks factors, evaluation of Euroscore and long term results. Eur J Cardiothorac Surg 27(2):276–280PubMedCrossRef
6.
go back to reference Grossi EA, Schwartz CF, Yu PJ, Jorde UP, Crooke GA, Grau JB et al (2008) High-risk aortic valve replacement: are the outcomes as bad as predicted? Ann Thorac Surg 85(1):102–106PubMedCrossRef Grossi EA, Schwartz CF, Yu PJ, Jorde UP, Crooke GA, Grau JB et al (2008) High-risk aortic valve replacement: are the outcomes as bad as predicted? Ann Thorac Surg 85(1):102–106PubMedCrossRef
7.
go back to reference Grube E, Schuler G, Buellesfeld L, Gerckens U, Linke A, Wenaweser P et al (2007) Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome. J Am Coll Cardiol 50(1):69–76PubMedCrossRef Grube E, Schuler G, Buellesfeld L, Gerckens U, Linke A, Wenaweser P et al (2007) Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome. J Am Coll Cardiol 50(1):69–76PubMedCrossRef
8.
go back to reference Gummert JF, Funkat A, Beckmann A, Hekmat K, Ernst M, Krian A (2006) Cardiac surgery in Germany during 2005: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 54(5):362–371PubMedCrossRef Gummert JF, Funkat A, Beckmann A, Hekmat K, Ernst M, Krian A (2006) Cardiac surgery in Germany during 2005: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 54(5):362–371PubMedCrossRef
9.
go back to reference Gummert JF, Funkat A, Beckmann A, Schiller W, Hekmat K, Ernst M et al (2007) Cardiac surgery in Germany during 2006: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 55(6):343–350PubMedCrossRef Gummert JF, Funkat A, Beckmann A, Schiller W, Hekmat K, Ernst M et al (2007) Cardiac surgery in Germany during 2006: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 55(6):343–350PubMedCrossRef
10.
go back to reference Gummert JF, Funkat A, Krian A (2005) Cardiac surgery in Germany during 2004: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 53(6):391–399PubMedCrossRef Gummert JF, Funkat A, Krian A (2005) Cardiac surgery in Germany during 2004: a report on behalf of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 53(6):391–399PubMedCrossRef
11.
go back to reference Herbert MA, Prince SL, Williams JL, Magee MJ, Mack MJ (2004) Are unaudited records from an outcomes registry database accurate? Ann Thorac Surg 77(6):1960–1964PubMedCrossRef Herbert MA, Prince SL, Williams JL, Magee MJ, Mack MJ (2004) Are unaudited records from an outcomes registry database accurate? Ann Thorac Surg 77(6):1960–1964PubMedCrossRef
12.
go back to reference Mesana T (2008) High-risk cardiac surgery: clinical judgment prevails on risk stratification. Curr Opin Cardiol 23(2):97–98PubMedCrossRef Mesana T (2008) High-risk cardiac surgery: clinical judgment prevails on risk stratification. Curr Opin Cardiol 23(2):97–98PubMedCrossRef
13.
go back to reference Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R (1999) European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 16(1):9–13PubMedCrossRef Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R (1999) European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg 16(1):9–13PubMedCrossRef
14.
go back to reference Parsonnet V, Dean D, Bernstein AD (1989) A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. Circulation 79(6 Pt 2):I3–12PubMed Parsonnet V, Dean D, Bernstein AD (1989) A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. Circulation 79(6 Pt 2):I3–12PubMed
15.
go back to reference Roques F, Michel P, Goldstone AR, Nashef SA (2003) The logistic EuroSCORE. Eur Heart J 24(9):881–882PubMedCrossRef Roques F, Michel P, Goldstone AR, Nashef SA (2003) The logistic EuroSCORE. Eur Heart J 24(9):881–882PubMedCrossRef
16.
go back to reference Roques F, Nashef SA, Michel P, Gauducheau E, de Vincentiis C, Baudet E et al (1999) Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients. Eur J Cardiothorac Surg 15(6):816–822PubMedCrossRef Roques F, Nashef SA, Michel P, Gauducheau E, de Vincentiis C, Baudet E et al (1999) Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patients. Eur J Cardiothorac Surg 15(6):816–822PubMedCrossRef
17.
go back to reference Sack S, Kahlert P, Khandanpour S, Naber C, Philipp S, Mohlenkamp S et al (2008) Revival of an old method with new techniques: balloon aortic valvuloplasty of the calcified aortic stenosis in the elderly. Clin Res Cardiol 97(5):288–297PubMedCrossRef Sack S, Kahlert P, Khandanpour S, Naber C, Philipp S, Mohlenkamp S et al (2008) Revival of an old method with new techniques: balloon aortic valvuloplasty of the calcified aortic stenosis in the elderly. Clin Res Cardiol 97(5):288–297PubMedCrossRef
18.
go back to reference Zingone B, Pappalardo A, Dreas L (2004) Logistic versus additive EuroSCORE. A comparative assessment of the two models in an independent population sample. Eur J Cardiothorac Surg 26(6):1134–1140PubMedCrossRef Zingone B, Pappalardo A, Dreas L (2004) Logistic versus additive EuroSCORE. A comparative assessment of the two models in an independent population sample. Eur J Cardiothorac Surg 26(6):1134–1140PubMedCrossRef
Metadata
Title
EuroSCORE overestimates the risk of cardiac surgery: results from the national registry of the German Society of Thoracic and Cardiovascular Surgery
Authors
J. F. Gummert
A. Funkat
B. Osswald
A. Beckmann
W. Schiller
A. Krian
F. Beyersdorf
A. Haverich
J. Cremer
Publication date
01-06-2009
Publisher
D. Steinkopff-Verlag
Published in
Clinical Research in Cardiology / Issue 6/2009
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-009-0010-8

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