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International Journal of Colorectal Disease

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Open Access 01-01-2021 | Colectomy | Original Article

Validation of the German Classification of Diverticular Disease (VADIS)—a prospective bicentric observational study

Authors: Johannes C. Lauscher, Johan F. Lock, Katja Aschenbrenner, Rahel M. Strobel, Marja Leonhardt, Andrea Stroux, Benjamin Weixler, Christoph-Thomas Germer, Martin E. Kreis

Published in: International Journal of Colorectal Disease | Issue 1/2021

Abstract

Purpose

The German Classification of Diverticular Disease was introduced a few years ago. The aim of this study was to determine whether Classification of Diverticular Disease enables an exact stratification of different types of diverticular disease in terms of course and treatment.

Methods

This was a prospective, bicentric observational trial. Patients aged ≥ 18 years with diverticular disease were prospectively included. The primary endpoint was the rate of recurrence within 2 year follow-up. Secondary outcome measures were Gastrointestinal Quality of Life Index, Quality of life measured by SF-36, frequency of gastrointestinal complaints, and postoperative complications.

Results

A total of 172 patients were included. After conservative management, 40% of patients required surgery for recurrence in type 1b vs. 80% in type 2a/b (p = 0.04). Sixty percent of patients with type 2a (micro-abscess) were in need of surgery for recurrence vs. 100% of patients with type 2b (macro-abscess) (p = 0.11). Patients with type 2a reached 123 ± 15 points in the Gastrointestinal Quality of Life Index compared with 111 ± 14 in type 2b (p = 0.05) and higher scores in the “Mental Component Summary” scale of SF-36 (52 ± 10 vs. 43 ± 13; p = 0.04). Patients with recurrent diverticulitis without complications (type 3b) had less often painful constipation (30% vs. 73%; p = 0.006) when they were operated compared with conservative treatment.

Conclusion

Differentiation into type 2a and 2b based on abscess size seems reasonable as patients with type 2b required surgery while patients with type 2a may be treated conservatively. Sigmoid colectomy in patients with type 3b seems to have gastrointestinal complaints during long-term follow-up.

Trial registration

https://www.drks.de ID: DRKS00005576

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Title: Validation of the German Classification of Diverticular Disease (VADIS)—a prospective bicentric observational study
Authors: Johannes C. Lauscher
Johan F. Lock
Katja Aschenbrenner
Rahel M. Strobel
Marja Leonhardt
Andrea Stroux
Benjamin Weixler
Christoph-Thomas Germer
Martin E. Kreis
Publication date: 01-01-2021
Publisher: Springer Berlin Heidelberg
Keywords: Colectomy
Colectomy
Diverticulitis
Published in: International Journal of Colorectal Disease / Issue 1/2021
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI: https://doi.org/10.1007/s00384-020-03721-9

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Springer Medicine

Validation of the German Classification of Diverticular Disease (VADIS)—a prospective bicentric observational study

Abstract

Purpose

Methods

Results

Conclusion

Trial registration

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Trial registration

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