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Published in: International Journal of Colorectal Disease 12/2009

01-12-2009 | Original Article

Treatment of grade III and IV haemorrhoidal disease with PPH or THD. A randomized trial on postoperative complications and short-term results

Authors: Sebastiaan Festen, M. J. van Hoogstraten, A. A. W. van Geloven, M. F. Gerhards

Published in: International Journal of Colorectal Disease | Issue 12/2009

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Abstract

Purpose

Haemorrhoidal disease is a frequently occurring entity in the western world. The Procedure for prolapse and haemorrhoids (PPH) and transanal haemorrhoidal dearterialisation (THD) are the most important surgical treatments that respect normal anal anatomy. This is the first randomized trial that compares both techniques in the treatment of grade III and IV haemorrhoids.

Methods

Patients with grade III or IV haemorrhoids were randomized between PPH and THD. Patients were seen after 1 week, 3 weeks and 6 weeks postoperatively. Primary endpoint was resolved symptoms 6 weeks postoperatively. Secondary endpoints were pain, measured with a visual analogue scale (VAS) after 1 day, 1 week and 3 weeks, and complications

Results

Eighteen patients were allocated to PPH versus 23 to THD. Success rates after 6 weeks were 83% in the PPH group versus 78% in the THD group. VAS scores were significantly lower after 1 day and 1 week in the THD group, but equalled out after 3 weeks. Twelve percent of the patients after PPH and 4% after THD needed an urgent readmission to treat an acute bleeding. Overall complication rates did not differ significantly.

Conclusion

Both PPH and THD are safe treatments for grade III and IV haemorrhoids with acceptable complication rates and good short-term results. THD might be the preferred treatment because it carries the similar complication rate and short-term results, but results in less postoperative pain when compared with PPH. Moreover, it is a less invasive, more easily learned and less costly procedure.
Literature
1.
go back to reference Kaidar-Person O, Person B, Wexner SD (2007) Hemorrhoidal disease: a comprehensive review. J Am Coll Surg 204(1):102–117CrossRefPubMed Kaidar-Person O, Person B, Wexner SD (2007) Hemorrhoidal disease: a comprehensive review. J Am Coll Surg 204(1):102–117CrossRefPubMed
3.
go back to reference MacRae HM, McLeod RS (1997) Comparison of hemorrhoidal treatments: a meta-analysis. Can J Surg 40(1):14–17PubMed MacRae HM, McLeod RS (1997) Comparison of hemorrhoidal treatments: a meta-analysis. Can J Surg 40(1):14–17PubMed
4.
go back to reference Longo A (2002) Stapled anopexy and stapled hemorrhoidectomy: two opposite concepts and procedures. Dis Colon Rectum 45(4):571–572CrossRefPubMed Longo A (2002) Stapled anopexy and stapled hemorrhoidectomy: two opposite concepts and procedures. Dis Colon Rectum 45(4):571–572CrossRefPubMed
5.
go back to reference Pescatori M, Aigner F (2007) Stapled transanal rectal mucosectomy ten years after. Tech Coloproctol 11(1):1–6CrossRefPubMed Pescatori M, Aigner F (2007) Stapled transanal rectal mucosectomy ten years after. Tech Coloproctol 11(1):1–6CrossRefPubMed
6.
go back to reference Ganio E, Altomare DF, Milito G, Gabrielli F, Canuti S (2007) Long-term outcome of a multicentre randomized clinical trial of stapled haemorrhoidopexy versus Milligan-Morgan haemorrhoidectomy. Br J Surg 94(8):1033–1037CrossRefPubMed Ganio E, Altomare DF, Milito G, Gabrielli F, Canuti S (2007) Long-term outcome of a multicentre randomized clinical trial of stapled haemorrhoidopexy versus Milligan-Morgan haemorrhoidectomy. Br J Surg 94(8):1033–1037CrossRefPubMed
7.
go back to reference Tjandra JJ, Chan MK (2007) Systematic review on the procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy). Dis Colon Rectum 50(6):878–892CrossRefPubMed Tjandra JJ, Chan MK (2007) Systematic review on the procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy). Dis Colon Rectum 50(6):878–892CrossRefPubMed
8.
go back to reference Goldstein SD, Meslin KP, Mazza T, Isenberg GA, Fitzgerald J, Richards A et al (2007) Stapled hemorrhoidopexy: outcome assessment. Am Surg 73(7):733–736PubMed Goldstein SD, Meslin KP, Mazza T, Isenberg GA, Fitzgerald J, Richards A et al (2007) Stapled hemorrhoidopexy: outcome assessment. Am Surg 73(7):733–736PubMed
9.
go back to reference Giordano P, Gravante G, Sorge R, Ovens L, Nastro P (2009) Long-term outcomes of stapled hemorrhoidopexy vs conventional hemorrhoidectomy: a meta-analysis of randomized controlled trials. Arch Surg 144(3):266–272CrossRefPubMed Giordano P, Gravante G, Sorge R, Ovens L, Nastro P (2009) Long-term outcomes of stapled hemorrhoidopexy vs conventional hemorrhoidectomy: a meta-analysis of randomized controlled trials. Arch Surg 144(3):266–272CrossRefPubMed
10.
go back to reference Thaha MA, Campbell KL, Kazmi SA, Irvine LA, Khalil A, Binnie NR et al (2009) Prospective randomised multi-centre trial comparing the clinical efficacy, safety and patient acceptability of circular stapled anopexy with closed diathermy haemorrhoidectomy. Gut 58(5):668–678CrossRefPubMed Thaha MA, Campbell KL, Kazmi SA, Irvine LA, Khalil A, Binnie NR et al (2009) Prospective randomised multi-centre trial comparing the clinical efficacy, safety and patient acceptability of circular stapled anopexy with closed diathermy haemorrhoidectomy. Gut 58(5):668–678CrossRefPubMed
11.
go back to reference Bona S, Battafarano F, Fumagalli RU, Zago M, Rosati R (2008) Stapled anopexy: postoperative course and functional outcome in 400 patients. Dis Colon Rectum 51(6):950–955CrossRefPubMed Bona S, Battafarano F, Fumagalli RU, Zago M, Rosati R (2008) Stapled anopexy: postoperative course and functional outcome in 400 patients. Dis Colon Rectum 51(6):950–955CrossRefPubMed
12.
go back to reference Ceci F, Picchio M, Palimento D, Cali B, Corelli S, Spaziani E (2008) Long-term outcome of stapled hemorrhoidopexy for Grade III and Grade IV hemorrhoids. Dis Colon Rectum 51(7):1107–1112CrossRefPubMed Ceci F, Picchio M, Palimento D, Cali B, Corelli S, Spaziani E (2008) Long-term outcome of stapled hemorrhoidopexy for Grade III and Grade IV hemorrhoids. Dis Colon Rectum 51(7):1107–1112CrossRefPubMed
13.
go back to reference Fueglistaler P, Guenin MO, Montali I, Kern B, Peterli R, von Flue M et al (2007) Long-term results after stapled hemorrhoidopexy: high patient satisfaction despite frequent postoperative symptoms. Dis Colon Rectum 50(2):204–212CrossRefPubMed Fueglistaler P, Guenin MO, Montali I, Kern B, Peterli R, von Flue M et al (2007) Long-term results after stapled hemorrhoidopexy: high patient satisfaction despite frequent postoperative symptoms. Dis Colon Rectum 50(2):204–212CrossRefPubMed
14.
go back to reference Kanellos I, Zacharakis E, Kanellos D, Pramateftakis MG, Tsachalis T, Betsis D (2006) Long-term results after stapled haemorrhoidopexy for third-degree haemorrhoids. Tech Coloproctol 10(1):47–49CrossRefPubMed Kanellos I, Zacharakis E, Kanellos D, Pramateftakis MG, Tsachalis T, Betsis D (2006) Long-term results after stapled haemorrhoidopexy for third-degree haemorrhoids. Tech Coloproctol 10(1):47–49CrossRefPubMed
15.
go back to reference Zacharakis E, Kanellos D, Pramateftakis MG, Kanellos I, Angelopoulos S, Mantzoros I et al (2007) Long-term results after stapled haemorrhoidopexy for fourth-degree haemorrhoids: a prospective study with median follow-up of 6 years. Tech Coloproctol 11(2):144–147CrossRefPubMed Zacharakis E, Kanellos D, Pramateftakis MG, Kanellos I, Angelopoulos S, Mantzoros I et al (2007) Long-term results after stapled haemorrhoidopexy for fourth-degree haemorrhoids: a prospective study with median follow-up of 6 years. Tech Coloproctol 11(2):144–147CrossRefPubMed
16.
go back to reference Brown S, Baraza W, Shorthouse A (2007) Total rectal lumen obliteration after stapled haemorrhoidopexy: a cautionary tale. Tech Coloproctol 11(4):357–358CrossRefPubMed Brown S, Baraza W, Shorthouse A (2007) Total rectal lumen obliteration after stapled haemorrhoidopexy: a cautionary tale. Tech Coloproctol 11(4):357–358CrossRefPubMed
17.
go back to reference Brusciano L, Ayabaca SM, Pescatori M, Accarpio GM, Dodi G, Cavallari F et al (2004) Reinterventions after complicated or failed stapled hemorrhoidopexy. Dis Colon Rectum 47(11):1846–1851CrossRefPubMed Brusciano L, Ayabaca SM, Pescatori M, Accarpio GM, Dodi G, Cavallari F et al (2004) Reinterventions after complicated or failed stapled hemorrhoidopexy. Dis Colon Rectum 47(11):1846–1851CrossRefPubMed
18.
go back to reference Cipriani S, Pescatori M (2002) Acute rectal obstruction after PPH stapled haemorrhoidectomy. Colorectal Dis 4(5):367–370CrossRefPubMed Cipriani S, Pescatori M (2002) Acute rectal obstruction after PPH stapled haemorrhoidectomy. Colorectal Dis 4(5):367–370CrossRefPubMed
19.
go back to reference Filingeri V, Gravante G (2005) The last images. Pneumoretroperitoneum, pneumomediastinum and subcutaneous emphysema of the neck after stapled hemorrhoidopexy. Tech Coloproctol 9(1):86CrossRefPubMed Filingeri V, Gravante G (2005) The last images. Pneumoretroperitoneum, pneumomediastinum and subcutaneous emphysema of the neck after stapled hemorrhoidopexy. Tech Coloproctol 9(1):86CrossRefPubMed
20.
go back to reference Pescatori M, Gagliardi G (2008) Postoperative complications after procedure for prolapsed hemorrhoids (PPH) and stapled transanal rectal resection (STARR) procedures. Tech Coloproctol 12(1):7–19CrossRefPubMed Pescatori M, Gagliardi G (2008) Postoperative complications after procedure for prolapsed hemorrhoids (PPH) and stapled transanal rectal resection (STARR) procedures. Tech Coloproctol 12(1):7–19CrossRefPubMed
21.
go back to reference Ripetti V, Caricato M, Arullani A (2002) Rectal perforation, retropneumoperitoneum, and pneumomediastinum after stapling procedure for prolapsed hemorrhoids: report of a case and subsequent considerations. Dis Colon Rectum 45(2):268–270CrossRefPubMed Ripetti V, Caricato M, Arullani A (2002) Rectal perforation, retropneumoperitoneum, and pneumomediastinum after stapling procedure for prolapsed hemorrhoids: report of a case and subsequent considerations. Dis Colon Rectum 45(2):268–270CrossRefPubMed
22.
go back to reference Sileri P, Stolfi VM, Franceschilli L, Perrone F, Patrizi L, Gaspari AL (2008) Reinterventions for specific technique-related complications of stapled haemorrhoidopexy (SH): a critical appraisal. J Gastrointest Surg 12(11):1866–1872CrossRefPubMed Sileri P, Stolfi VM, Franceschilli L, Perrone F, Patrizi L, Gaspari AL (2008) Reinterventions for specific technique-related complications of stapled haemorrhoidopexy (SH): a critical appraisal. J Gastrointest Surg 12(11):1866–1872CrossRefPubMed
23.
go back to reference Wong LY, Jiang JK, Chang SC, Lin JK (2003) Rectal perforation: a life-threatening complication of stapled hemorrhoidectomy: report of a case. Dis Colon Rectum 46(1):116–117CrossRefPubMed Wong LY, Jiang JK, Chang SC, Lin JK (2003) Rectal perforation: a life-threatening complication of stapled hemorrhoidectomy: report of a case. Dis Colon Rectum 46(1):116–117CrossRefPubMed
24.
go back to reference Morinaga K, Hasuda K, Ikeda T (1995) A novel therapy for internal hemorrhoids: ligation of the hemorrhoidal artery with a newly devised instrument (Moricorn) in conjunction with a Doppler flowmeter. Am J Gastroenterol 90(4):610–613PubMed Morinaga K, Hasuda K, Ikeda T (1995) A novel therapy for internal hemorrhoids: ligation of the hemorrhoidal artery with a newly devised instrument (Moricorn) in conjunction with a Doppler flowmeter. Am J Gastroenterol 90(4):610–613PubMed
25.
go back to reference Dal Monte PP, Tagariello C, Sarago M, Giordano P, Shafi A, Cudazzo E et al (2007) Transanal haemorrhoidal dearterialisation: nonexcisional surgery for the treatment of haemorrhoidal disease. Tech Coloproctol 11(4):333–338CrossRefPubMed Dal Monte PP, Tagariello C, Sarago M, Giordano P, Shafi A, Cudazzo E et al (2007) Transanal haemorrhoidal dearterialisation: nonexcisional surgery for the treatment of haemorrhoidal disease. Tech Coloproctol 11(4):333–338CrossRefPubMed
26.
go back to reference Faucheron JL, Gangner Y (2008) Doppler-guided hemorrhoidal artery ligation for the treatment of symptomatic hemorrhoids: early and three-year follow-up results in 100 consecutive patients. Dis Colon Rectum 51(6):945–949CrossRefPubMed Faucheron JL, Gangner Y (2008) Doppler-guided hemorrhoidal artery ligation for the treatment of symptomatic hemorrhoids: early and three-year follow-up results in 100 consecutive patients. Dis Colon Rectum 51(6):945–949CrossRefPubMed
27.
go back to reference Wilkerson PM, Strbac M, Reece-Smith H, Middleton SB (2009) Doppler-guided haemorrhoidal artery ligation: long-term outcome and patient satisfaction. Colorectal Dis 11(4):394–400CrossRefPubMed Wilkerson PM, Strbac M, Reece-Smith H, Middleton SB (2009) Doppler-guided haemorrhoidal artery ligation: long-term outcome and patient satisfaction. Colorectal Dis 11(4):394–400CrossRefPubMed
28.
go back to reference Walega P, Scheyer M, Kenig J, Herman RM, Arnold S, Nowak M et al (2008) Two-center experience in the treatment of hemorrhoidal disease using Doppler-guided hemorrhoidal artery ligation: functional results after 1-year follow-up. Surg Endosc 22(11):2379–2383CrossRefPubMed Walega P, Scheyer M, Kenig J, Herman RM, Arnold S, Nowak M et al (2008) Two-center experience in the treatment of hemorrhoidal disease using Doppler-guided hemorrhoidal artery ligation: functional results after 1-year follow-up. Surg Endosc 22(11):2379–2383CrossRefPubMed
29.
go back to reference Jayaraman S, Colquhoun PH, Malthaner RA (2007) Stapled hemorrhoidopexy is associated with a higher long-term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. Dis Colon Rectum 50(9):1297–1305CrossRefPubMed Jayaraman S, Colquhoun PH, Malthaner RA (2007) Stapled hemorrhoidopexy is associated with a higher long-term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. Dis Colon Rectum 50(9):1297–1305CrossRefPubMed
30.
go back to reference Schmidt J, Dogan N, Langenbach R, Zirngibl H (2009) Fecal urge incontinence after stapled anopexia for prolapse and hemorrhoids: a prospective, observational study. World J Surg 33(2):355–364CrossRefPubMed Schmidt J, Dogan N, Langenbach R, Zirngibl H (2009) Fecal urge incontinence after stapled anopexia for prolapse and hemorrhoids: a prospective, observational study. World J Surg 33(2):355–364CrossRefPubMed
Metadata
Title
Treatment of grade III and IV haemorrhoidal disease with PPH or THD. A randomized trial on postoperative complications and short-term results
Authors
Sebastiaan Festen
M. J. van Hoogstraten
A. A. W. van Geloven
M. F. Gerhards
Publication date
01-12-2009
Publisher
Springer-Verlag
Published in
International Journal of Colorectal Disease / Issue 12/2009
Print ISSN: 0179-1958
Electronic ISSN: 1432-1262
DOI
https://doi.org/10.1007/s00384-009-0803-2

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