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Pediatric Surgery International

Published in:

01-05-2013 | Original Article

Primary pediatric cardiac malignancies: the SEER experience

Authors: James S. Davis, Bassan J. Allan, Eduardo A. Perez, Holly L. Neville, Juan E. Sola

Published in: Pediatric Surgery International | Issue 5/2013

Abstract

Purpose

Pediatric cardiac malignancies are exceedingly rare. We sought to examine demographics, presentation, and outcomes for this pathology.

Methods

The SEER registry from 1973 to 2008 was queried for all patients <20 years of age with cardiac malignancies.

Results

A total of 25 pediatric patients were identified with primary cardiac malignancies, with age-adjusted incidence of 0.00686 per 100,000 United States population. Median age at diagnosis was 10 years. The majority of patients were adolescent (n = 13, 52 %), Caucasian (n = 17, 68 %) and males (n = 14, 56 %). The most common histology was soft tissue sarcoma (n = 10, 40%), followed by non-Hodgkin lymphoma and teratoma (both n = 3, 12 %). Six patients presented with distant disease. More than half of patients (n = 16, 64 %) underwent surgical resection, while four patients (16 %) underwent radiation. The mean survival time for the cohort was 47 ± 67 months, with 14 (56 %) patients dying over the study period. Lymphomas had significantly longer survival than other malignancies (108 ± 66 vs. 36 ± 66, p = 0.03), while lack of surgical treatment was associated with worse survival (p = 0.016).

Conclusions

Primary malignant cardiac tumors are exceedingly rare in pediatric patients. They are most commonly soft tissue sarcomas and lymphomas demonstrated longer survival.

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Title: Primary pediatric cardiac malignancies: the SEER experience
Authors: James S. Davis
Bassan J. Allan
Eduardo A. Perez
Holly L. Neville
Juan E. Sola
Publication date: 01-05-2013
Publisher: Springer-Verlag
Published in: Pediatric Surgery International / Issue 5/2013
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-013-3261-4

At a glance: The STEP trials

Springer Medicine

Primary pediatric cardiac malignancies: the SEER experience

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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