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01-03-2018 | Case-Based Update

Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition

Authors: Matheus Fernando Manzolli Ballestero, Dinark Conceição Viana, Thiago Lyrio Teixeira, Marcelo Volpon Santos, Ricardo Santos de Oliveira

Published in: Child's Nervous System | Issue 3/2018

Abstract

Background

Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring after injury to the dentato-rubro-olivary pathway (“Guillain-Mollaret triangle”). The majority of studies have described HOD resulting from posterior fossa (PF) hemorrhage or infarction. HOD in patients undergoing PF surgery has not been well characterized. These lesions are rare and symptomatic children with HOD are even more uncommon. The purpose of this study was to evaluate HOD that develops after PF operations in children.

Materials and methods

A literature review was carried out describing 37 pediatric cases of HOD in 13 articles. In addition, two new cases of our own experience were included.

Conclusions

HOD is a rare complication related after PF tumors surgery and symptoms may be misdiagnosed with pediatric cerebellar mutism syndrome. Children with HOD usually do not develop palatal tremor but ataxia is common.

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Title: Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition
Authors: Matheus Fernando Manzolli Ballestero
Dinark Conceição Viana
Thiago Lyrio Teixeira
Marcelo Volpon Santos
Ricardo Santos de Oliveira
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 3/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-017-3705-6

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Hypertrophic olivary degeneration in children after posterior fossa surgery. An underdiagnosed condition

Abstract

Background

Materials and methods

Conclusions

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Springer Medicine

Abstract

Background

Materials and methods

Conclusions

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