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Child's Nervous System
Published in: Child's Nervous System 3/2014

01-03-2014 | Review Paper

Cause and outcome of cerebellar mutism: evidence from a systematic review

Authors: Rosa Reed-Berendt, Bob Phillips, Susan Picton, Paul Chumas, Daniel Warren, John H. Livingston, Ellen Hughes, Matthew C. H. J. Morrall

Published in: Child's Nervous System | Issue 3/2014

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Abstract

Purpose

Cerebellar mutism is a serious neurosurgical complication after posterior fossa surgery, but the cause, incidence and outcome remain incompletely defined. The aim of this paper was to identify and review all reports of this phenomenon to better delineate and improve the evidence base.

Methods

A systematic search and retrieval of databases was conducted using advanced search techniques. Review/outcomes criteria were developed, and study quality was determined.

Results

The retrieval identified 2,281 papers of which 96 were relevant, identifying 650 children with cerebellar mutism. Causative factors, clinical features and outcomes were reported variably; papers focussed on multiple areas, the majority reporting incidence in single or series of case studies with little or no analysis further than description.

Conclusions

The complexity and variability of data reporting, likely contributing factors and outcomes make cerebellar mutism difficult to predict in incidence and the degree of impact that may ensue. A clear and accepted universal definition would help improve reporting, as would the application of agreed outcome measures. Clear and consistent reporting of surgical technique remains absent. Recommendations for practice are provided.
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Metadata
Title
Cause and outcome of cerebellar mutism: evidence from a systematic review
Authors
Rosa Reed-Berendt
Bob Phillips
Susan Picton
Paul Chumas
Daniel Warren
John H. Livingston
Ellen Hughes
Matthew C. H. J. Morrall
Publication date
01-03-2014
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 3/2014
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-014-2356-0

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