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Child's Nervous System

Published in:

01-03-2018 | Original Paper

The incidence of brainstem primitive neuroectodermal tumors of childhood based on SEER data

Authors: Omar Chamdine, Ghada Ahmad Saad Elhawary, Ahmad Samir Alfaar, Ibrahim Qaddoumi

Published in: Child's Nervous System | Issue 3/2018

Abstract

Purpose

Incidence of BS primitive neuroectodermal tumors (BS-PNET) in children is not reported to date. Our main objectives were to estimate the incidence and report the outcome of BS-PNET in children.

Methods

Data were collected using the Surveillance Epidemiology and End Results cancer registry.

Results

From 1973 to 2013, we identified 83 pediatric patients (aged 0–21 years). Patients were divided into two age groups (0–3 years and 4–21 years). Median overall survival was 53 months. Patients in the older age group had a significant survival advantage (P < 0.001), as did those who received three modalities of therapy (surgery, chemotherapy, and radiation therapy) (P < 0.001) and patients with gross or subtotal tumor resection (P < 0.001).

Conclusions

This study presents the first estimate of incidence and the largest cohort of pediatric BS-PNETs to date. A high index of suspicion of BS-PNET in similar cases is crucial for diagnosis, treatment, and outcome.

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Title: The incidence of brainstem primitive neuroectodermal tumors of childhood based on SEER data
Authors: Omar Chamdine
Ghada Ahmad Saad Elhawary
Ahmad Samir Alfaar
Ibrahim Qaddoumi
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: Child's Nervous System / Issue 3/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-017-3687-4

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

The incidence of brainstem primitive neuroectodermal tumors of childhood based on SEER data

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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