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Child's Nervous System
Published in: Child's Nervous System 8/2013

01-08-2013 | Case Report

Significance of radical resection for pilomyxoid astrocytoma of the cerebellum: a case report and review of the literature

Authors: Atsushi Okano, Soichi Oya, Naoaki Fujisawa, Tsukasa Tsuchiya, Masahiro Indo, Takumi Nakamura, Han Soo Chang, Toru Matsui

Published in: Child's Nervous System | Issue 8/2013

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Abstract

Background

Pilomyxoid astrocytoma (PMA) was recently classified as a variant of pilocytic astrocytoma (PA) with significantly more aggressive clinical features than those of PA. Like PAs, PMAs frequently arise in the chiasmatic/hypothalamic regions. The cerebellum is also a common site of occurrence for PAs but not for PMAs.

Case description

We present the case of a 31-month-old boy with cerebellar PMA that showed rapid regrowth during the 3 months following the first subtotal resection. Gross total resection was achieved in the second surgery, followed by radiation to the tumor bed.

Results

During follow-up over the next 12 years, there has been no evidence of recurrence on magnetic resonance imaging.

Conclusions

Although the prognosis of cerebellar PMAs remains unknown because of the paucity of cases, the relevant literature reports a more favorable outcome for cerebellar PMAs than for PMAs occurring at other locations. The results of this case study and a review of the relevant literature advocate radical resection, sometimes involving multiple surgeries, for cerebellar PMAs because gross total or near total resection is more feasible in the cerebellum than in other locations.
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Metadata
Title
Significance of radical resection for pilomyxoid astrocytoma of the cerebellum: a case report and review of the literature
Authors
Atsushi Okano
Soichi Oya
Naoaki Fujisawa
Tsukasa Tsuchiya
Masahiro Indo
Takumi Nakamura
Han Soo Chang
Toru Matsui
Publication date
01-08-2013
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 8/2013
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-013-2082-z

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