Skip to main content
Top
Published in: Child's Nervous System 7/2004

01-07-2004 | Original Paper

Cerebral toxocariasis: a possible cause of epileptic seizure in children

Authors: Heidi Bächli, Jean Claude Minet, Otmar Gratzl

Published in: Child's Nervous System | Issue 7/2004

Login to get access

Abstract

Introduction

Toxocariasis is a worldwide human helminthiasis, which is mostly asymptomatic and caused by toxocara canis, a roundworm in dogs. These can cause visceral larva migrans syndrome in humans who ingest contaminated soil. CNS manifestation with a focal mass lesion is very rare, seizures often being the first symptom.

Case report

We describe an 11-year-old girl presenting with a generalized epileptic seizure and eosinophilia in blood. Under antibiotic therapy under the assumption of toxoplasmosis the lesion did not decrease and surgical resection was considered. We used computer-assisted surgery (CAS) for careful tissue resection. Postoperatively the diagnosis of toxocariasis was confirmed and albendozole medication was administered for 7 days. The patient developed well without neurological deficits or seizures.

Conclusion

We conclude that although neurological involvement is rare in toxocariasis, a cerebral infection in a child with epileptic seizures and eosinophilia should be considered.
Literature
1.
go back to reference Arpino C, Gattinara GC, Piergili D, Curato P (1990) Toxocara infection and epilepsy in children: a case-control study. Epilepsia 31:33–36PubMed Arpino C, Gattinara GC, Piergili D, Curato P (1990) Toxocara infection and epilepsy in children: a case-control study. Epilepsia 31:33–36PubMed
2.
go back to reference Dousset V, Sibon I, Menegon P (2003) Case no 6. Cerebral vasculitis due to toxocara canis (or catis origin). J Radiol 84:89–91PubMed Dousset V, Sibon I, Menegon P (2003) Case no 6. Cerebral vasculitis due to toxocara canis (or catis origin). J Radiol 84:89–91PubMed
3.
go back to reference Goffette S, Jeanjean A, Duprez T, Bigaignon G, Sindic C (2000) Eosinophilic pleocytosis and myelitis related to toxocara canis infection. Eur J Neurol 7:703–706CrossRefPubMed Goffette S, Jeanjean A, Duprez T, Bigaignon G, Sindic C (2000) Eosinophilic pleocytosis and myelitis related to toxocara canis infection. Eur J Neurol 7:703–706CrossRefPubMed
4.
go back to reference Gould M, Newell S, Green SH, Gorge RH (1985) Toxocariasis and eosinophilic meningitis. Br Med J 291:1239–1240 Gould M, Newell S, Green SH, Gorge RH (1985) Toxocariasis and eosinophilic meningitis. Br Med J 291:1239–1240
5.
go back to reference Hill IR, Denham DA, Scholtz CL (1985) Toxocara canis larvae in the brain of a British child. Trans R Soc Trop Med Hyg 79:351–354CrossRefPubMed Hill IR, Denham DA, Scholtz CL (1985) Toxocara canis larvae in the brain of a British child. Trans R Soc Trop Med Hyg 79:351–354CrossRefPubMed
6.
go back to reference Kumar J, Kimm J (1994) MR in Toxocara canis myelopathy. Am J Neuroradiol 15:1918–1920PubMed Kumar J, Kimm J (1994) MR in Toxocara canis myelopathy. Am J Neuroradiol 15:1918–1920PubMed
8.
go back to reference Nelson I, Frost JL, Schochet SS Jr (1990) Unsuspected cerebral Toxocara infection in a fire victim. Clin Neuropathol 9:106–108PubMed Nelson I, Frost JL, Schochet SS Jr (1990) Unsuspected cerebral Toxocara infection in a fire victim. Clin Neuropathol 9:106–108PubMed
10.
go back to reference Oujamaa L, Sibon I, Vital A, Menegon P (2003) Cerebral vasculitis secondary to toxocara canis and fasciola hepatica co-infestation. Rev Neurol (Paris) 159:447–450 Oujamaa L, Sibon I, Vital A, Menegon P (2003) Cerebral vasculitis secondary to toxocara canis and fasciola hepatica co-infestation. Rev Neurol (Paris) 159:447–450
11.
go back to reference Richartz E, Buchkremer G (2002) Cerebral toxocariasis: a rare cause of cognitive disorders. A contribution to differential dementia diagnosis. Nervenarzt 73:458–462CrossRef Richartz E, Buchkremer G (2002) Cerebral toxocariasis: a rare cause of cognitive disorders. A contribution to differential dementia diagnosis. Nervenarzt 73:458–462CrossRef
12.
13.
go back to reference Ruttinger P, Hadidi H (1991) MRI in cerebral toxocaral disease. J Neurol Neurosurg Psychiatry 54:361–362PubMed Ruttinger P, Hadidi H (1991) MRI in cerebral toxocaral disease. J Neurol Neurosurg Psychiatry 54:361–362PubMed
14.
go back to reference Sommer C, Ringelstein EB, Biniek R, Glockner WM (1994) Adult Toxocara canis encephalitis. J Neurol Neurosurg Psychiatry 57:229–231PubMed Sommer C, Ringelstein EB, Biniek R, Glockner WM (1994) Adult Toxocara canis encephalitis. J Neurol Neurosurg Psychiatry 57:229–231PubMed
15.
go back to reference Strupp M, Pfister HW, Eichenlaub S, Arbusow V (1999) Meningomyelitis in a case of toxocariasis with markedly isolated CSF eosinophilia and an MRI-documented related thoracic cord lesion. J Neurol 246:741–744CrossRefPubMed Strupp M, Pfister HW, Eichenlaub S, Arbusow V (1999) Meningomyelitis in a case of toxocariasis with markedly isolated CSF eosinophilia and an MRI-documented related thoracic cord lesion. J Neurol 246:741–744CrossRefPubMed
16.
go back to reference Vidal JE, Sztajnbok J, Seguro AC (2003) Eosinophilic meningoencephalitis due to Toxocara canis: case report and review of the literature. Am J Trop Med Hyg 69:341–343PubMed Vidal JE, Sztajnbok J, Seguro AC (2003) Eosinophilic meningoencephalitis due to Toxocara canis: case report and review of the literature. Am J Trop Med Hyg 69:341–343PubMed
17.
go back to reference Viovy A, Jofrè L, Noemi I, Erazo R, Cerva J (1999) Granuloma cerebral por toxocara: comunicacion de un caso clinico. Rev Chil Infectol 15:312–316 Viovy A, Jofrè L, Noemi I, Erazo R, Cerva J (1999) Granuloma cerebral por toxocara: comunicacion de un caso clinico. Rev Chil Infectol 15:312–316
18.
go back to reference Westermann B, Hauser H (2000) Online head motion tracking applied to the patient registration problem. Comput Aided Surg 5:137–147CrossRefPubMed Westermann B, Hauser H (2000) Online head motion tracking applied to the patient registration problem. Comput Aided Surg 5:137–147CrossRefPubMed
19.
go back to reference Xinou E, Lefkopoulos A, Gelagoti M, Drevelegas A, Diakou A, Milon Dimitriadis AS (2003) CT and MRI imaging findings in cerebral toxocaral disease. Am J Neuroradiol 24:714–718PubMed Xinou E, Lefkopoulos A, Gelagoti M, Drevelegas A, Diakou A, Milon Dimitriadis AS (2003) CT and MRI imaging findings in cerebral toxocaral disease. Am J Neuroradiol 24:714–718PubMed
20.
go back to reference Zachariah SB, Zachariah B, Varghese R (1994) Neuroimaging studies of cerebral “visceral larva migrans” syndrome. J Neuroimaging 4:39–40PubMed Zachariah SB, Zachariah B, Varghese R (1994) Neuroimaging studies of cerebral “visceral larva migrans” syndrome. J Neuroimaging 4:39–40PubMed
Metadata
Title
Cerebral toxocariasis: a possible cause of epileptic seizure in children
Authors
Heidi Bächli
Jean Claude Minet
Otmar Gratzl
Publication date
01-07-2004
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 7/2004
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-004-0963-x

Other articles of this Issue 7/2004

Child's Nervous System 7/2004 Go to the issue