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Published in: Child's Nervous System 7-8/2003

01-08-2003 | Original Paper

The Chiari II malformation: cause and impact

Authors: David G. McLone, Mark S. Dias

Published in: Child's Nervous System | Issue 7-8/2003

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Abstract

Introduction

It is the Chiari II malformation and its effects that determine the quality of life of the individual born with spina bifida.

Discussion

The cause of this malformation has been a source of debate for many years. Understanding the cause enables strategies for the management of problems created by this malformation to be developed. An open neural tube defect allows fluid to escape from the cranial vesicles, altering the intracranial environment and leads to all of the brain changes seen in the Chiari II malformation. Decompression of the intracranial vesicles causes overcrowding, decrease in the size of the third ventricle, and changes in the fetal skull. It also permanently links the intracranial ventricular system to the spinal cord central canal.
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Metadata
Title
The Chiari II malformation: cause and impact
Authors
David G. McLone
Mark S. Dias
Publication date
01-08-2003
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 7-8/2003
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-003-0792-3

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