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Published in: World Journal of Urology 9/2018

01-09-2018 | Invited Review

Thulium laser VapoResection of the prostate versus traditional transurethral resection of the prostate or transurethral plasmakinetic resection of prostate for benign prostatic obstruction: a systematic review and meta-analysis

Authors: Zheng Deng, Menghao Sun, Yiping Zhu, Jian Zhuo, Fujun Zhao, Shujie Xia, Bangmin Han, Thomas R. W. Herrmann

Published in: World Journal of Urology | Issue 9/2018

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Abstract

Purpose

To compare the efficacy and safety of thulium laser VapoResection of the prostate (ThuVaRP) versus standard traditional transurethral resection of the prostate (TURP) or plasmakinetic resection of prostate (PKRP) for benign prostatic obstruction.

Methods

Systematic searches were performed in the Medline, EMBASE, the Cochrane Library, Web of Science, and CNKI in December 2017. The outcomes of demographic and clinical characteristics, perioperative variables, complications, and postoperative efficacy including International Prostate Symptom Score (IPSS), quality of life (QoL), maximum flow rate (Qmax), and postvoid residual (PVR) were assessed.

Results

16 studies were selected in the meta-analysis including nine randomized controlled trials (RCTs) and seven non-RCTs. Among of them, nine studies compared ThuVaRP with PKRP, while seven studies compared ThuVaRP with TURP. It seemed that ThuVaRP needed longer operation time than TURP (WMD = 6.41, 95% CI 1.38–11.44, p = 0.01) and PKRP (WMD = 10.15, 95% CI 5.20–15.10, p < 0.0001). ThuVaRP was associated with less serum hemoglobin decreased, catheterization time, and the length of hospital stay compared with TURP (WMD = − 0.58, 95% CI − 0.77 to 0.38, p < 0.00001; WMD = − 1.89, 95% CI − 2.67 to 1.11, p < 0.00001; WMD = − 2.25, 95% CI − 2.91 to 1.60, p < 0.00001) and PKRP (WMD = − 0.28, 95% CI − 0.46 to 0.10, p = 0.002; WMD = − 1.88, 95% CI − 2.87 to 0.89, p = 0.0002; WMD = − 2.08, 95% CI − 2.63 to 1.54, p<0.00001). According to our assessment, there was no significantly difference in postoperative efficacy.

Conclusions

The pooled data indicated that ThuVaRP had a nearly efficacy to TURP and PKRP based on IPSS, QoL, Qmax, and PVR. Although ThuVaRP was associated with longer operation time, it got distinct superiority on serum hemoglobin decreased, catheterization time, and hospital stay.
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Metadata
Title
Thulium laser VapoResection of the prostate versus traditional transurethral resection of the prostate or transurethral plasmakinetic resection of prostate for benign prostatic obstruction: a systematic review and meta-analysis
Authors
Zheng Deng
Menghao Sun
Yiping Zhu
Jian Zhuo
Fujun Zhao
Shujie Xia
Bangmin Han
Thomas R. W. Herrmann
Publication date
01-09-2018
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 9/2018
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-018-2287-6

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