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01-01-2018 | Original Article

Standard vs. anatomical 180-W GreenLight laser photoselective vaporization of the prostate: a propensity score analysis

Authors: Luca Cindolo, Cosimo De Nunzio, Francesco Greco, Paolo Destefanis, Franco Bergamaschi, Giovanni Ferrari, Giuseppe Fasolis, Fabiano Palmieri, Claudio Divan, Rino Oriti, Lorenzo Ruggera, Andrea Tubaro, Claudio Dadone, Gaetano De Rienzo, Antonio Frattini, Vincenzo Mirone, Luigi Schips, Members of Green Laser Italian Group

Published in: World Journal of Urology | Issue 1/2018

Abstract

Purpose

To compare the efficacy, safety, Patient Global Impression of Improvement (PGI-I), and complications rates after 180-W GreenLight laser (180-W GL laser) standard and anatomical photoselective vaporization (sPVP and aPVP).

Methods

Within a multi-institutional database, we identified patients who underwent sPVP or aPVP to relief BPH symptoms. IPSS, Q _max, and prostate-specific antigen (PSA) were measured at baseline and during the follow-up. PGI-I score as well as early and late complications were recorded at follow-up visits. Log-binomial and multivariable proportional odds regression models were fitted to estimate the effect of aPVP vs. sPVP on PGI-I as well as on early and late complication rates, before and after adjustment for propensity score.

Results

813 patients were included. Of those, the 50.4% underwent aPVP. Patients who underwent aPVP had larger prostate (64 vs. 55 mL, p < 0.001) and higher baseline PSA levels (3.1 vs. 2.5 ng/mL, p < 0.001). PGI-I score was signaled as very improved, improved, slightly improved, unchanged, or worsened in 55.5, 32.8, 8.3, 2.3, and 1.2% of the cases, respectively, with no differences according the technique used (p = 0.420). Acute urinary retention occurred in 9.2 vs. 8.9% of patients after aPVP vs. sPVP (p = 0.872). All models failed to find differences in: patients’ satisfaction (OR 1.19, p = 0.256), early complications (RR 0.93, p = 0.387), early urge/incontinence symptoms (RR 0.97, p = 0.814), and late complications rates (RR 0.70, p = 0.053), after aPVP vs. sPVP.

Conclusion

Our results showed similar functional results and complication rates after aPVP and sPVP. However, aPVP was used in larger prostates. Both techniques guarantee high patient’s satisfaction.

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Title: Standard vs. anatomical 180-W GreenLight laser photoselective vaporization of the prostate: a propensity score analysis
Authors: Luca Cindolo
Cosimo De Nunzio
Francesco Greco
Paolo Destefanis
Franco Bergamaschi
Giovanni Ferrari
Giuseppe Fasolis
Fabiano Palmieri
Claudio Divan
Rino Oriti
Lorenzo Ruggera
Andrea Tubaro
Claudio Dadone
Gaetano De Rienzo
Antonio Frattini
Vincenzo Mirone
Luigi Schips
Members of Green Laser Italian Group
Publication date: 01-01-2018
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 1/2018
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-017-2106-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Standard vs. anatomical 180-W GreenLight laser photoselective vaporization of the prostate: a propensity score analysis

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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